Mirtazapine acts as an alpha-2 adrenergic receptor (ADRA2) antagonist, causing the release of norepinephrine and serotonin in the brain. These neurotransmitters are essential in regulating mood and emotions. By increasing their release, mirtazapine helps to alleviate the symptoms of major depressive disorder, which has been marketed under various trade names such as Razapina and Reflex. Developed by Merck Sharp & Dohme, this drug was first approved in the United States, China, Germany, and South Korea.This drug is available in tablet form and should be taken orally. However, caution should be taken when using this drug as it may cause side effects such as drowsiness, weight gain, and dry mouth. Despite the possible side effects, mirtazapine has shown efficacy in the treatment of depression. Click on the image below to begin the exploration journey of Mirtazapine through the Synapse database!
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