Bio Sequence

Specific Nucleotide Sequence Searching and Finding

7 September 2023
3 min read

Q: Is it enough to only search for nucleotide sequences when searching for a specific nucleotide sequence?

A: Of course not. Not only do you need to search for the target nucleotide sequence, but you also need to search for its translated protein sequence. This is especially important when performing patent novelty searches or FTO studies. This is because some patents may indirectly protect or disclose their nucleotide sequences from the perspective of amino acid sequences.

For example, WO2013186563A2 claim 1 protects a nucleic acid molecule that has 85% homology with SEQ ID NO: 4 (amino acid sequence), so when querying the sequence, you need to translate the target nucleotide sequence into an amino acid sequence for retrieval.

Here, I recommend that you use the Patsnap Bio Sequence Database, where you can directly search for nucleotide/amino acid sequences. The database also offers a lot of small tools for sequence retrieval (click on 'Sequence Suite' in the left column of the database homepage), such as sequence format conversion, sequence translation, amino acid single-letter/three-letter conversion, etc.

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It is important to note that Patsnap Bio is the most extensive sequence search platform for the Patsnap database. It incorporates AI with human-curated data for comprehensive handling of protein and nucleotide sequence data plucked from global patents, biological periodicals, and public repositories. Essential biological sequences are manually annotated illuminating structural modifications to provide the most accurate sequence data and boost sequence retrieval efficiency.

 

Free registration is currently available to utilize the Bio biological sequence database: https://bio.patsnap.com. Act now to expedite your sequence search tasks.

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