Dicyclomine Hydrochloride, marketed as BENTYL, is an antispasmodic and anticholinergic medication that was approved for use in the USA in 1950 for the treatment of Irritable Bowel Syndrome but has since been withdrawn from the market. The drug is an antagonist of muscarinic acetylcholine receptors (mAChRs). Its chemical name is [bicyclohexyl]-1-carboxylic acid, 2-(diethylamino) ethyl ester, hydrochloride, with a molecular formula of C19H35NO2•HCl. BENTYL was manufactured by Allergan. As an antispasmodic agent, BENTYL worked by relaxing the muscles in the stomach and intestines, reducing symptoms such as abdominal pain and cramping. As an anticholinergic, BENTYL blocked the effects of acetylcholine, a neurotransmitter that plays a role in intestinal motility. Click on the image below to begin the exploration journey of Dicyclomine through the Synapse database!
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