| Synonyms Block, Nerve, Block;nerve, Blockade, Nerve + [40] | 
| Introduction Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain. | 
| Target | 
| Mechanism AChE inhibitors [+1]  | 
| Active Org. | 
| Originator Org. | 
| Active Indication | 
| Inactive Indication- | 
| Drug Highest PhaseApproved | 
| First Approval Ctry. / Loc. Australia | 
| First Approval Date20 Aug 2018 | 
| Target- | 
| Mechanism Muscle relaxation antagonists | 
| Active Org. | 
| Originator Org. | 
| Active Indication | 
| Inactive Indication | 
| Drug Highest PhaseApproved | 
| First Approval Ctry. / Loc. European Union [+3]  | 
| First Approval Date25 Jul 2008 | 
| Target | 
| Mechanism SCNA modulators | 
| Active Org. | 
| Originator Org. | 
| Active Indication | 
| Inactive Indication | 
| Drug Highest PhaseApproved | 
| First Approval Ctry. / Loc. United Kingdom [+8]  | 
| First Approval Date22 Apr 1996 | 
| Start Date01 Jan 2026 | 
| Sponsor / Collaborator | 
| Start Date01 Sep 2025 | 
| Sponsor / Collaborator | 
| Start Date01 Jul 2025 | 
| Sponsor / Collaborator | 
