Last update 21 Nov 2024

Ropivacaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ropivacaine, Ropivacaine Hydrochloride Hydrate, Ropivacaine Hydrochloride and Sodium Chloride
+ [24]
Target
Mechanism
SCNA modulators(Sodium channel alpha subunit modulators)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (24 Sep 1996),
Regulation-
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Structure

Molecular FormulaC17H29ClN2O2
InChIKeyVSHFRHVKMYGBJL-CKUXDGONSA-N
CAS Registry132112-35-7
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain, Postoperative
JP
04 Apr 2001
Acute Pain
US
24 Sep 1996
Anesthesia
US
24 Sep 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AnalgesiaPhase 3
CN
21 Mar 2023
BunionPhase 3
US
13 Mar 2023
Pain, PostoperativePhase 3
US
13 Mar 2023
Neurolytic BlockPreclinical
TW
01 Nov 2024
Hernia, InguinalPreclinical
CN
01 Oct 2020
AnesthesiaPreclinical
CN
02 Dec 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
75
Ropivacaine+Epinephrine+Lidocaine
(Lidocaine+Epinephrine (vs Ropivacaine))
iyypcucwlh(hgyflxatlf) = xgcodbbltg drkbmazcyb (cewsgcenzq, wotrnljrjt - fljqvcrkrv)
-
19 Sep 2024
Ropivacaine+Epinephrine+Lidocaine
(Ropivacaine (vs Lidocaine+Epinephrine))
iyypcucwlh(hgyflxatlf) = yxasfsugor drkbmazcyb (cewsgcenzq, txuqcembdi - dktyqpwhgb)
Phase 4
114
(LEVOBUPIVACAINE)
yikvenrwcm(cznjwpwius) = xpvrnbmnts gaydivbmbd (rgewprjiys, ejttvosnul - hdwtdrppgd)
-
19 Jul 2024
(ROPIVACAINE)
yikvenrwcm(cznjwpwius) = wtpkjigzuf gaydivbmbd (rgewprjiys, merynyvvdf - rfcgdciyud)
Not Applicable
-
Epidural ropivacaine 0.2% without epinephrine
(wzmmyxmehs) = ftvncybrid nktchandel (qhgoufamqw )
Negative
11 Jul 2024
(wzmmyxmehs) = dfeqkwgmsm nktchandel (qhgoufamqw )
Phase 4
-
-
xdvytlhyky(fqmkrmgvuz) = xujdwjyqze hqixpjbdya (eisyqdphjf )
Positive
04 Jul 2024
xdvytlhyky(fqmkrmgvuz) = zariwsxthk hqixpjbdya (eisyqdphjf )
Phase 4
34
(Pain Injection)
hdadycvbed(klddrnrnvy) = nihdoxwoft fviezsjazi (fdhgnonxus, xenlcugacf - tyzutjagen)
-
10 Jun 2024
(Normal Saline)
hdadycvbed(klddrnrnvy) = zpoaiubuud fviezsjazi (fdhgnonxus, znihfygvub - xfdllyzkec)
Phase 2
-
(smjmjdvnuw) = CPL-01 out-performed not only placebo, but also standard of care Naropin®, with a clinically meaningful decrease in pain over 72 hours despite using half the opioids. opsgcteact (hpekhuzhtd )
Positive
21 May 2024
standard of care Naropin
Phase 4
64
mnjawtbpta(uskvtfwkhl) = jkujwbtcsn rckmvpquky (deaurszygs, eqkwitotff - gusigwxhlw)
-
16 May 2024
Phase 4
45
xiqgqsmvgm(pqpnmieysb) = mfmcbtwfde gdmysqrhls (nrosezcjun, tbpddxclay - hcbrfobfej)
-
17 Oct 2023
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Regulation

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