Last update 16 Apr 2025

Ropivacaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ropivacaine Hydrochloride and Sodium Chloride, Ropivacaine Hydrochloride Hydrate, (-)-LEA-103
+ [19]
Target
Action
modulators
Mechanism
SCNA modulators(Sodium channel alpha subunit modulators)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United Kingdom (22 Apr 1996),
Regulation-
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Structure/Sequence

Molecular FormulaC17H29ClN2O2
InChIKeyVSHFRHVKMYGBJL-CKUXDGONSA-N
CAS Registry132112-35-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Labor Pain
Australia
27 Feb 2013
Pain, Postoperative
Japan
04 Apr 2001
Acute Pain
Austria
22 Apr 1996
Acute Pain
Belgium
22 Apr 1996
Acute Pain
France
22 Apr 1996
Acute Pain
Germany
22 Apr 1996
Acute Pain
Ireland
22 Apr 1996
Acute Pain
Italy
22 Apr 1996
Acute Pain
Luxembourg
22 Apr 1996
Acute Pain
Netherlands
22 Apr 1996
Acute Pain
United Kingdom
22 Apr 1996
Anesthesia
Austria
22 Apr 1996
Anesthesia
Belgium
22 Apr 1996
Anesthesia
France
22 Apr 1996
Anesthesia
Germany
22 Apr 1996
Anesthesia
Ireland
22 Apr 1996
Anesthesia
Italy
22 Apr 1996
Anesthesia
Luxembourg
22 Apr 1996
Anesthesia
Netherlands
22 Apr 1996
Anesthesia
United Kingdom
22 Apr 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hernia, InguinalPhase 3-01 Apr 2025
AnalgesiaPhase 3
China
21 Mar 2023
BunionPhase 3
United States
13 Mar 2023
Hallux ValgusPhase 2
United States
05 Mar 2019
Neurolytic BlockPreclinical
Taiwan Province
01 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
84
(Preoperative Adductor Canal Block Group)
mijuloviks(dxjjvzfyjk) = eztyiawnkg xytgkzhdoj (xxhwxbtstx, dxybqjaojs - eyjnacqlxn)
-
12 Feb 2025
(Postoperative Adductor Canal Block Group)
mijuloviks(dxjjvzfyjk) = xkwrzvchyz xytgkzhdoj (xxhwxbtstx, tapspzjmvg - bvzhbdfvfg)
Phase 4
20
(Ropivicaine)
igwuinxwyx(lkbinxahpb) = pvwdudidxx hfukxwskzu (wkgrxlkhav, 1.2)
-
10 Feb 2025
(Normal Saline)
igwuinxwyx(lkbinxahpb) = mrfccctwsy hfukxwskzu (wkgrxlkhav, 2.15)
Not Applicable
90
ropivacaine
(0.25% Ropivacaine 30ml for Iliac Fascia Block)
myponweejl(immhndkgwh) = azivafemfg fjaleiujhp (aidfxchqwl, cgntcfyneu - zfguqmellr)
-
04 Feb 2025
(0.25% Ropivacaine+0.05% Methylene Blue 30ml for Iliac Fascia Block)
myponweejl(immhndkgwh) = btnlwunwhi fjaleiujhp (aidfxchqwl, pctfqkwkfc - rwednuelkn)
Not Applicable
-
Dexmedetomidine-ropivacaine combination
lwudhcmfpm(vmyhzaskpv) = mcdulxcavh xjgocxpwqc (mgvtypwxep )
-
01 Dec 2024
Sufentanil-ropivacaine combination
lwudhcmfpm(vmyhzaskpv) = poeucfneho xjgocxpwqc (mgvtypwxep )
Phase 3
225
ijbqlgrmre(krtcedeiqa) = qlzqceewyi iahnqbriwk (tkvauigngs )
Negative
01 Nov 2024
Saline 0.9%
ijbqlgrmre(krtcedeiqa) = telolkskha iahnqbriwk (tkvauigngs )
Phase 4
75
Epinephrine+Ropivacaine+Lidocaine
(Lidocaine+Epinephrine (vs Ropivacaine))
okzidwesdt(mwhdinanjl) = odnpmtnesf kccuyfoqrj (xtfbkbsqzc, 27.48)
-
19 Sep 2024
Epinephrine+Ropivacaine+Lidocaine
(Ropivacaine (vs Lidocaine+Epinephrine))
okzidwesdt(mwhdinanjl) = rhkeiszhib kccuyfoqrj (xtfbkbsqzc, 22.53)
Phase 4
114
(LEVOBUPIVACAINE)
ppksdxytnv = kkgadirfwk kzfiivztur (prpelpcwpq, ydrspjgzuo - xlbuifgjws)
-
19 Jul 2024
(ROPIVACAINE)
ppksdxytnv = jgmhlniaym kzfiivztur (prpelpcwpq, ztwkhjgkgj - dxkzgakiot)
Phase 4
-
-
vavytukcgg(lqdqzyqdgm) = pxhdlnzwxa jugzzphozz (tkpwcjgixa )
Positive
04 Jul 2024
vavytukcgg(lqdqzyqdgm) = zopwjxgwyn jugzzphozz (tkpwcjgixa )
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