评价格隆溴铵新斯的明注射液在中国全麻术后患者中单次静脉给药后的安全性、有效性和药代动力学特征的研究
[Translation] A study to evaluate the safety, efficacy and pharmacokinetic characteristics of glycopyrrolate neostigmine injection after a single intravenous administration in Chinese patients undergoing general anesthesia after surgery
主要目的:
评价不同剂量下,格隆溴铵新斯的明注射液在中国全麻术后患者中逆转非去极化肌肉松弛药残留肌松作用时的安全性;
评价不同剂量下,格隆溴铵新斯的明注射液在中国全麻术后患者中逆转非去极化肌肉松弛药残留肌松作用时单次静脉给药的药代动力学特征。
次要目的:
评价不同剂量下,格隆溴铵新斯的明注射液在中国全麻术后患者中逆转非去极化肌肉松弛药残留肌松作用时的初步有效性。
[Translation] Primary objective:
To evaluate the safety of glycopyrrolate neostigmine injection at different doses in reversing the residual muscle relaxant effect of non-depolarizing muscle relaxants in Chinese patients after general anesthesia;
To evaluate the pharmacokinetic characteristics of glycopyrrolate neostigmine injection at different doses in reversing the residual muscle relaxant effect of non-depolarizing muscle relaxants in Chinese patients after general anesthesia.
Secondary objective:
To evaluate the preliminary effectiveness of glycopyrrolate neostigmine injection at different doses in reversing the residual muscle relaxant effect of non-depolarizing muscle relaxants in Chinese patients after general anesthesia.
The optimal dose of neostigmine for antagonizing cisatracurium-induced mild (TOFr=0.2) muscle relaxation block in elderly patients: a randomized controlled trial
/ SuspendedNot ApplicableIIT The recovery effect of antagonitst of muscle relaxant in pediatric patients
Start Date06 Dec 2019 |
Sponsor / Collaborator- |
100 Clinical Results associated with Reversal of non depolarizing muscle relaxants
100 Translational Medicine associated with Reversal of non depolarizing muscle relaxants
0 Patents (Medical) associated with Reversal of non depolarizing muscle relaxants