A Multi Centre, Randomized, Double Masked, Placebo-Controlled, Parallel-Group, Phase III Comparison Study to Assess Efficacy and Safety of Bibrocathol 2% Eye Ointment (Posiformin 2%) in the treatment of Chronic Blepharoconjuctivitis. - NA

Start Date13 Sep 2022

Sponsor / Collaborator-

NCT03975374 / Unknown statusEarly Phase 1

Efficacy and Safety of Tobradex Eye Drop Suspension vs Tobramycin/Dexamethasone Ophthalmic Suspension

The objective of the study is to compare and describe efficacy and safety of Tobradex ophthalmic suspension versus generic Tobramycin/dexamethasone Suspension in treatment of Blepharoconjuctivitis through clinical parameters

Start Date15 Jun 2019

Sponsor / Collaborator

Sutphin Drugs Inc

ISRCTN14084351 / CompletedPhase 3

A multi-centre, randomized, double-masked, placebo-controlled, parallel-group, phase III study to assess efficacy and safety of Bibrocathol 2% eye ointment (Bibrocathol-POS 2%) in the treatment of chronic blepharoconjunctivitis

Start Date15 Jan 2018

Sponsor / Collaborator

URSAPHARM Arzneimittel GmbH & Co. KG

100 Clinical Results associated with Unspecified blepharoconjunctivitis

100 Translational Medicine associated with Unspecified blepharoconjunctivitis

0 Patents (Medical) associated with Unspecified blepharoconjunctivitis

379

Literatures (Medical) associated with Unspecified blepharoconjunctivitis

16 May 2024·Cureus

Bilateral Ophthalmomyiasis Externa of Lid by Musca domestica: A Rare Presentation

Article

Author: Sune, Mona P ; Sune, Manjiri P ; Mahajan, Shital M ; Sune, Pradeep

A case of severe blepharoconjunctivitis in the last three weeks diagnosed the slit lamp as external ophthalmomyiasis. On ocular examination, numerous pupae were present on the lid margins, firmly adhering to the lid lashes bilaterally. All of them were removed mechanically under topical anesthesia. They were 67 in number. Healing occurred without any complications. In such cases of blepharoconjunctivitis, physicians should consider the possibility of ophthalmomyiasis externa, especially in places where high numbers of livestock are found. Otherwise, there is a chance of missing the diagnosis, which can be met with a more serious condition called ophthalmomyiasis interna.

13 May 2024·Cureus

Human Subcutaneous Dirofilariasis Behind a Blepharoconjunctivitis: A Case Report and Review of the Literature

Article

Author: Morosanu, Sergiu ; Morosanu, Valentin ; Don, Roman

The diagnosis of skin lesions involving the eyes can be challenging, especially when uncommon etiologies are considered. We present a case of a 52-year-old female initially diagnosed with blepharoconjunctivitis but later found to have a subcutaneous heartworm infection. The patient experienced recurrent episodes of unilateral palpebral edema, pain, pruritus, and a sensation of a foreign body in her eye. Upon examination, a vermiform structure with peristaltic movements was observed, raising suspicion of subcutaneous dirofilariasis and prompting further investigations. Serological tests confirmed the presence of anti-Dirofilaria spp. antibodies. Surgical removal of the worm led to the resolution of symptoms. This case highlights the importance of considering uncommon etiologies, such as subcutaneous heartworm infection, in patients presenting with atypical migratory skin lesions or ocular manifestations when there is no definite diagnosis and the condition does not respond to usual medical treatment.

01 May 2024·European Journal of Ophthalmology

Liposomal ozonated oil effectiveness in the signs and symptoms of blepharitis in usual clinical practice

Article

Author: Benítez-Del-Castillo, Jose Manuel

Purpose To analyze the efficacy of liposomal ozonated oil (Ozonest®) treatment, in patients with blepharitis or blepharoconjunctivitis, in improving the signs and symptoms of the pathology. Methods Exploratory, open-label, prospective, single-arm, pre-post comparative pilot study in usual clinical practice, in 20 patients with blepharitis/blepharoconjunctivitis, receiving treatment with liposomal ozonated oil, one drop in each eye, 4 times a day, for 28 days. Main purpose was to assess whether there was a clinically improvement in the blepharitis specific BLISS questionnaire score. Changes in the 12-item OSDI, in eyelid signs of blepharitis assessed by the physicians were also evaluated among other tests, and there was also a subjective evaluation of the treatment by patients. Results The BLISS score significantly improved from 16.4 before treatment to 11.8 after treatment ( p < 0.05). The OSDI score was also significantly improved from 27.5 before treatment to 20.5 after treatment ( p < 0.05). All tests conducted before and after treatment showed significant improvement ( p < 0.05), except for NIBUT. The treatment received a score of 7 out of 10 by the patients. There were no adverse events in any patient. Conclusion Liposomal ozonated oil treatment showed good efficacy in improving the signs and symptoms of blepharitis/blepharoconjunctivitis, satisfaction of patients, and good safety and tolerability.

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