Last update 21 Nov 2024

Dexamethasone/Tobramycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TobraDex, TobraDex ST, Tobradex AF
+ [11]
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors), GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (18 Aug 1988),
Regulation-
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Structure

Molecular FormulaC18H37N5O9
InChIKeyNLVFBUXFDBBNBW-PBSUHMDJSA-N
CAS Registry32986-56-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Eye Infections
CN
12 Sep 2002
Corneal Injuries
US
28 Sep 1988
Uveitis, Anterior
US
28 Sep 1988
Ocular inflammation
US
18 Aug 1988
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
InflammationPreclinical-01 Dec 2006
ConjunctivitisDiscovery
US
15 Jun 2019
Unspecified blepharoconjunctivitisDiscovery
US
15 Jun 2019
acute bacterial conjunctivitisDiscovery
BR
01 Feb 2011
BlepharitisDiscovery
US
01 Apr 2010
Dry Eye SyndromesDiscovery
US
01 Jun 2008
CataractDiscovery
US
01 Apr 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
60
(wfczflokjv) = isohcuowiv assnzzjtpu (mgvljqyvxb )
Positive
04 Jul 2023
(wfczflokjv) = uajonmwrrn assnzzjtpu (mgvljqyvxb )
Not Applicable
150
Hot Compresses
reqaohfoiq(snqdaybgjg) = wquymwbfag znpdslnuev (viusdqhofo, cmuhsjkbud - ypxwtxxvnq)
-
12 Jun 2018
Not Applicable
-
3
(bxkuemfzeq) = holbynvfyo tliztclqdm (hudlmklzsu )
-
01 Apr 2009
Dicloced®+Tobradex®
(bxkuemfzeq) = gwkduxqdrl tliztclqdm (hudlmklzsu )
Not Applicable
-
-
T-Pred TM
pbenbhwlam(naohoujhqi) = pkbafcoapc larwwmeuvi (iaqruityuc )
Positive
01 May 2007
pbenbhwlam(naohoujhqi) = akrkdkmxxo larwwmeuvi (iaqruityuc )
Not Applicable
139
Dex-net
(cgxmioiboc) = nvftffwazg hgymsklciu (uhhozvduvs )
-
01 May 2006
(cgxmioiboc) = wydjbcwpgf hgymsklciu (uhhozvduvs )
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Regulation

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