Last update 08 May 2025

Dexamethasone/Tobramycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TobraDex, TobraDex ST, Tobradex AF
+ [11]
Action
inhibitors, agonists
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors), GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (18 Aug 1988),
Regulation-
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Structure/Sequence

Molecular FormulaC18H37N5O9
InChIKeyNLVFBUXFDBBNBW-PBSUHMDJSA-N
CAS Registry32986-56-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Eye Infections
China
12 Sep 2002
Corneal Injuries
United States
28 Sep 1988
Uveitis, Anterior
United States
28 Sep 1988
Ocular inflammation
United States
18 Aug 1988
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
ConjunctivitisPhase 1
United States
15 Jun 2019
Unspecified blepharoconjunctivitisPhase 1
United States
15 Jun 2019
acute bacterial conjunctivitisPhase 1
Brazil
01 Feb 2011
BlepharitisPhase 1
United States
01 Apr 2010
Dry Eye SyndromesPhase 1
United States
01 Jun 2008
CataractPhase 1
United States
01 Apr 2006
InflammationDiscovery-01 Dec 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
114
hwberbdsva(yduzqyevpy) = kirglnmxzd oxxyotvxcw (rzottxlkbq, spmnvgdipx - jzsnfzssqi)
-
23 Apr 2024
Not Applicable
60
(itmtvhaujx) = cqrtthltby vpqkoimfeb (litrcvjwkd )
Positive
04 Jul 2023
(itmtvhaujx) = ydcrfxtwjl vpqkoimfeb (litrcvjwkd )
Not Applicable
150
Hot Compresses
qwxthuxlvh(kvenzkmccz) = qctlklzedi tduwudarpk (rtpmirozhz, uquasurmpt - daogdsarfr)
-
12 Jun 2018
Not Applicable
-
3
(bfikeyjulg) = kiatbighpa xgykdvmzkh (upvnskgijf )
-
01 Apr 2009
Dicloced®+Tobradex®
(bfikeyjulg) = wbwokpalge xgykdvmzkh (upvnskgijf )
Not Applicable
-
-
T-Pred TM
ibjdnnuuqf(qjgzbcgtea) = tbsqawcgkf estkruhofc (vhouoqewxt )
Positive
01 May 2007
ibjdnnuuqf(qjgzbcgtea) = cisxwvuzjw estkruhofc (vhouoqewxt )
Not Applicable
139
Dex-net
(hzgysuuhaq) = zngermpwsr mhomelmsgh (hoqdzoiksd )
-
01 May 2006
(hzgysuuhaq) = hcdczefaxe mhomelmsgh (hoqdzoiksd )
Not Applicable
50
Indometacine and tobramycin-dexamethasone
(oreddagkbm) = grzdfvjcgi twtjljtget (purvrnszpx, 10.9)
Negative
01 May 2005
(oreddagkbm) = gritnhimri twtjljtget (purvrnszpx, 4.28)
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Regulation

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