Last update 01 Nov 2024

Dexamethasone/Tobramycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TobraDex, TobraDex ST, Tobradex AF
+ [11]
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors), GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (18 Aug 1988),
Regulation-
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Structure

Molecular FormulaC18H37N5O9
InChIKeyNLVFBUXFDBBNBW-PBSUHMDJSA-N
CAS Registry32986-56-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Eye Infections
CN
12 Sep 2002
Corneal Injuries
US
28 Sep 1988
Uveitis, Anterior
US
28 Sep 1988
Ocular inflammation
US
18 Aug 1988
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ConjunctivitisPhase 1
US
15 Jun 2019
Unspecified blepharoconjunctivitisPhase 1
US
15 Jun 2019
acute bacterial conjunctivitisPhase 1
BR
01 Feb 2011
BlepharitisPhase 1
US
01 Apr 2010
Dry Eye SyndromesPhase 1
US
01 Jun 2008
CataractPhase 1
US
01 Apr 2006
InflammationIND Application-01 Dec 2006
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
60
(daankafczo) = yjikcxnwtz obgqbwaivt (fqcjzhpnrb )
Positive
04 Jul 2023
(daankafczo) = yhqxulbzqw obgqbwaivt (fqcjzhpnrb )
Not Applicable
150
Hot Compresses
gvysokeosy(cqkcfmmbuw) = zpzswhmsmq xcwrtsasse (jgpfcyrwuf, szumltnqld - nkazgjrekx)
-
12 Jun 2018
Not Applicable
-
3
(ywpkfsahfa) = wevvqxqfkd hatnoezswk (drrujpwoev )
-
01 Apr 2009
Dicloced®+Tobradex®
(ywpkfsahfa) = rgkgdyacrz hatnoezswk (drrujpwoev )
Not Applicable
-
-
T-Pred TM
svjgtfjida(ktbbgfsspa) = yberobkxda cpltvpszce (zsaulgnslc )
Positive
01 May 2007
svjgtfjida(ktbbgfsspa) = zzefrddgle cpltvpszce (zsaulgnslc )
Not Applicable
139
Dex-net
(auxufukrnk) = fniwsbcrfb ewdskdgrel (izashwomlr )
-
01 May 2006
(auxufukrnk) = ttonoviafk ewdskdgrel (izashwomlr )
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Regulation

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