Last update 01 Nov 2024

Fracture, segmental

Last update 01 Nov 2024

Basic Info

Synonyms

Fracture, segmental, Fracture, segmental (morphologic abnormality), Segmental fracture

Introduction

A type of fracture in which the same bone is fractured in two places, so there is a floating segment of bone. []

Drugs associated with Fracture, segmental

Mesenchymal Stem Cells(Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus)

Target-

Mechanism

Stem cell replacements

Active Org.

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Originator Org.

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Active Indication

Fracture, segmental

Inactive Indication-

Drug Highest PhasePhase 1/2

First Approval Ctry. / Loc.-

First Approval Date20 Jan 1800

Clinical Trials associated with Fracture, segmental

NCT05520125 / Not yet recruitingPhase 1/2IIT

Treatment of Patients With Segmental Bone Tissue Defects Using Mesenchymal Stem Cells Enriched by Extracellular Vesicles

Treatment of patients with segmental bone tissue defects using mesenchymal stem cells enriched by extracellular vesicles

Start Date01 Nov 2022

Sponsor / Collaborator

The National Academy of Sciences of Belarus

[+1]

100 Clinical Results associated with Fracture, segmental

100 Translational Medicine associated with Fracture, segmental

0 Patents (Medical) associated with Fracture, segmental

216

Literatures (Medical) associated with Fracture, segmental

01 Nov 2024·International Journal of Surgery Case Reports

Tibialis anterior and extensor hallucis longus tendon ruptures complicating a closed tibial fracture: A case report

Article

Author: Karami, Amin ; Sadighi, Mehrdad ; Ebrahimpour, Adel ; Pourmahmoudian, Mohammad ; Rad, Saber Barazandeh ; Kafiabadi, Meisam Jafari

INTRODUCTION AND IMPORTANCEAcute rupture of the tibialis anterior tendon and other tendons is an extremely rare injury. It is usually associated with minor trauma in older patients with medical comorbidity. Surgeons must be alert for rupture of these tendons which can complicate a closed tibial fracture.CASE PRESENTATIONA 19-year-old man was transferred to the emergency department with a segmental fracture at the lower third of his tibia. The patient could not actively dorsiflex his right ankle and first toe but was able to dorsiflex other toes actively. The tibialis anterior and extensor hallucis longus tendon were discovered torn at the same point, supposedly by a bone spike. The fracture was reduced and fixed and the tendons were repaired.CLINICAL DISCUSSIONA traumatic rupture of the tibialis anterior and extensor hallucis longus tendons occurs rarely in conjunction with or as a consequence of a bony fracture in closed trauma, with only a few cases documented in the literature. They typically occur as a result of direct blunt or penetrating injury. In three papers, the tibial fracture caused a direct rupture in the tendon. We believe that the tendons rubbing against the fractured edges of the segmental bone of the tibia led to the tendons tearing gradually.CONCLUSIONFurther investigation is needed for an evaluation of ankle and first toe dorsiflexion to check for a palpable gap in the soft tissues of a lower third tibial fracture. The tibialis anterior and other tendons can be located between the segment of the tibial fracture and ruptured.

01 Oct 2024·Journal of Stomatology, Oral and Maxillofacial Surgery

New dimensions in alveolar fracture treatment: Open reduction and internal fixation by minimally invasive approach combined with computer-assisted surgery

Article

Author: Li, Zhi ; Lin, Yu-Xin ; Cao, Lei-Ming ; Zhang, Ze-Xing ; Lv, Kun

Alveolar fractures are a common type of maxillofacial trauma, and the conventional treatment involves closed reduction and dental splinting fixation. However, closed treatment is not suitable for some complex segmental alveolar fractures. In this case report, we introduce an innovative method for segmental alveolar fracture by using open reduction and internal fixation by minimally invasive approach combined with computer-assisted surgery. In this case, the new dimensions in the treatment followed AO principles of fracture management, achieving anatomical reduction of the fracture, absolute stability of the fracture ends, proper preservation of vascular supply to soft tissues and bone, and promoting recovery through early postoperative functional training. This case provides new insights into the treatment of the complex segmental alveolar fractures with tenuous vascular supply and cannot be treated by conventional splinting fixation.

01 Aug 2024·Trauma Case Reports

A case of damage control after polytrauma and bilateral femur fracture

Article

Author: Oulianski, Maria ; Avraham, Dana ; Herman, Amir

IntroductionMulti-trauma patients require a multidisciplinary team, especially in the presence of various body systems injuries. The evaluation focuses on the decision regarding the DCO and ETC approaches.Case presentationA 24-year-old male patient with Glasgow Coma Score 8, arrived at the emergency room, followed by ATLS protocol. Orthopedic trauma included D8 vertebra unstable burst fracture, right open femur shaft fracture, left closed midshaft femur fracture, and right tibial plateau fracture of the knee.Case summaryA hemodynamically stable patient with bilateral femur fractures is directed toward the DCO approach.DiscussionAn initial treatment for an external fixator across the knee on the right leg and a spine fusion and decompression of D5-10 surgery was made on the day of admission. Definitive fixation and conversion to internal fixators were done on day 9 after the accident. Postoperative drop-foot injury was seen in the right leg. A Masquelet technique was applied for the right femur segmental fracture due to gaps.ConclusionDCO may be employed to temporarily stabilize fractures, allowing the patient to recover from other life-threatening injuries before definitive fixation. Further secondary procedures, such as the Masquelet technique, should be considered to optimize the results. Long-term follow-up and rehabilitation are part of recovery, aiming to optimize functional recovery and improve the patient's quality of life.

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