Last update 01 Nov 2024

Pseudohypoaldosteronism

Basic Info

Synonyms
Autosomal dominant PHA1, Autosomal dominant pseudohypoaldosteronism type 1, Autosomal recessive PHA1
+ [83]
Introduction
A heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. Congenital forms are rare autosomal disorders characterized by neonatal hypertension, HYPERKALEMIA, increased RENIN activity and ALDOSTERONE concentration. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after KIDNEY TRANSPLANTATION.

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