Spinal Dysraphism

Funding awards for new patient-centered CER address a range of pediatric and adult health challenges WASHINGTON, April 8, 2025 /PRNewswire/ -- Every day, millions of Americans make health care decisions without enough information to fully understand the trade-offs between approaches to care and make informed choices for themselves or their families. To help address these information gaps, the Patient-Centered Outcomes Research Institute (PCORI) has announced funding for new patient-centered comparative clinical effectiveness research (CER) studies across a range of conditions. These studies will help provide patients and caregivers with the evidence needed to make more informed health and health care decisions and more effectively manage their health. Continue Reading The Patient-Centered Outcomes Research Institute (PCORI) has announced funding for new patient-centered comparative clinical effectiveness research (CER) studies across a range of conditions. These studies will help provide patients and caregivers with the evidence needed to make more informed health and health care decisions and more effectively manage their health. (PRNewsfoto/Patient-Centered Outcomes Research Institute) With the latest funding awards through the Patient-Centered Outcomes Research Institute’s Health Systems Implementation Initiative, 31 health systems are implementing findings of PCORI-funded comparative clinical effectiveness research (CER) studies to improve care for adults and children across the nation. (PRNewsfoto/Patient-Centered Outcomes Research Institute) Research Funding Highlights Sixteen new patient-centered CER studies addressing a range of health challenges Among the CER studies, eight focused on long-term follow-up of patient-centered health outcomes Six additional health research studies focused on CER methods and engagement in science The newly awarded patient-centered CER studies include research comparing: Two durations of antibiotics for children hospitalized with common infections Treatments for neurodevelopmental differences in young children Interventions to treat pediatric anxiety Mammography with and without artificial intelligence assistance Care approaches for rare diseases such as spina bifida and amyotrophic lateral sclerosis Eight of the patient-centered CER studies will examine the long-term effects of treatments, interventions and programs previously studied in PCORI-funded CER, aiming to provide a more comprehensive understanding of the potential benefits and harms of these approaches. Additional research awards support four studies to improve patient-centered CER methods and two studies to strengthen the evidence base on effectively engaging patients and other health and health care decisionmakers through the design and conduct of patient-centered CER. Accelerating uptake of PCORI-funded research results PCORI also supports initiatives to accelerate the implementation of PCORI-funded CER results into clinical practice, addressing the often-cited 17-year gap between result publication and clinical practice adoption. Through its Health Systems Implementation Initiative (HSII), PCORI has announced 19 funding awards focused on: Improving hypertension diagnosis and management Electronic monitoring of patient-reported outcomes during cancer treatment Optimizing outpatient antibiotic prescribing for children with acute respiratory tract infections (ARTIs) With these new awards, HSII participant health systems have implementation projects across 31 states and the District of Columbia. These projects have the potential to impact care for 1.9 million patients across 3,800 care sites and include previously awarded PCORI-funded projects for intensive lifestyle treatment programs for weight loss as well as additional awards to improve antibiotic prescribing for children with ARTIs. See the full list of new research and HSII awards on PCORI's website. All award funding has been approved pending final PCORI contractual considerations. About PCORI The Patient-Centered Outcomes Research Institute (PCORI) is a nonprofit organization authorized by Congress to fund patient-centered comparative clinical effectiveness research (CER). CER compares two or more health care options, generating evidence about any differences in potential benefits or harms to empower patients, caregivers and other health care decision makers with information to make informed choices that reflect their needs and preferences. PCORI emphasizes the engagement of patients, caregivers and the broader health care community in all aspects of PCORI-funded research and research-related activities, including the dissemination and uptake of research findings. SOURCE Patient-Centered Outcomes Research Institute WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED

Celebrating 100 years of caring for childrenMONTREAL, Oct. 04, 2024 (GLOBE NEWSWIRE) -- The 36th edition of the Canada Shrine Bowl will take place on Saturday, October 5 at 1 p.m. at Concordia Stadium, 7200 Sherbrooke Street West in Montreal. Each year, the game raises awareness about our patients and the pediatric specialty care thousands of them receive annually. Shriners Children’s Canada will be celebrating its 100th anniversary this year and has provided pediatric specialty care to thousands of patients over that time. This year’s game will also feature two patient ambassadors, Finley and Émerick, to proudly represent the hospital. This year's matchup is between the Concordia University Stingers against the Sherbrooke University Vert & Or. The public is invited to attend this annual event in support of Shriners Hospitals for Children Canada. Kevin Regimbald, head coach of the Vert & Or, and Brad Collinson, head coach of the Concordia Stingers, are all set for this superb sporting match between the two teams. This year, Montreal Alouettes player, Kristian Matte, will be the guest of honor. Accompanied by the Karnak Shriners, he will co-chair the opening and closing ceremonies of the game. Finley Finley was born with congenital scoliosis, missing and misshapen vertebrae, along with several rib anomalies. In addition to these spinal conditions, she faces spina bifida occulta, ketotic hypoglycemia, and severe asthma. Despite these challenges, Finley has never let her diagnoses define her. Since the age of 1, she has been traveling from Calgary to Montreal to see Dr. Ouellet at Shriners Hospitals for Children Canada. Thanks to the expert care she receives, Finley can enjoy her favorite activities—swimming, biking, gymnastics, and dancing. Her greatest joy comes from doing handstands and cartwheels, proving that nothing can hold her back! Émerick Émerick, 8 years old, was diagnosed with cerebral palsy, which made it hard for him to move. After a long, three-year wait for surgery at another hospital, his family found hope at Shriners Hospitals for Children Canada, known for its quick and excellent care. Within months, Émerick had a life-changing surgery called selective dorsal rhizotomy, which has helped him gain independence. Now, he can kick a soccer ball, walk with special aids, and stand longer without support. In just six months, Émerick has made incredible progress, showing his determination and the amazing support he has received. The public is welcome to attend the Shrine Bowl. The doors will open at 11:00 am on Saturday, October 5. To purchase tickets, go to Stingers.ca | Buy Tickets. If you cannot attend the game but still wish to donate for our patients, you can send an e-transfer to moncontribution@shrinenet.org (include your full name and address to receive a tax receipt). About Shriners Hospitals for Children Canada Established in Montreal in 1925, Shriners Hospital for Children ─ Canada is the only Canadian facility within the extensive Shriners Hospitals network. A bilingual hospital, it offers ultra-specialized acute orthopedic care to children from Canada, the United States and around the world. The hospital's mission is to promote health and provide treatment and rehabilitation for infants, children and young adults with orthopedic and neuromuscular conditions such as scoliosis, osteogenesis imperfecta, clubfoot, hip dysplasia and cerebral palsy. The hospital is committed to excellence and innovation in clinical practice, research and education. Affiliated with McGill University, the hospital enables resident physicians and healthcare professionals to take advantage of its facilities on the Glen site to further their training and experience. In addition to offering a patient- and family-centered care environment, the hospital is present in communities across Canada through telemedicine, outreach clinics and satellite clinics. Laure Moureaux, Communications Advisor, Shriners Hospitals for Children Canada 514-282-7222 / Cell: 514-207-2267, lmoureaux@shrinenet.org Chloe Ricciardi, Public Relations, Concordia University 514-796-7969, chloe.ricciardi@concordia.ca

RESEARCH TRIANGLE PARK, N.C., Sept. 19, 2024 /PRNewswire/ -- Dignify Therapeutics (Dignify), a leading developer of therapies for bladder and bowel dysfunction, recently received two significant research grants from the NIH. These grants add to the previous $20 million in research funding the company has received to advance multiple therapeutics for bladder and bowel disorders. Grants include R43DK138600 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and R43AG088838 from the National Institute on Aging (NIA). Dr. Karl B. Thor, Chief Scientific Officer and Investigator on the grants indicated; "We are very grateful that multiple Institutes at the NIH support the severe, unmet, medical need for therapies to restore control of bladder and bowel dysfunction. These therapies are directed toward the elderly and people with neurological conditions such as spinal injury, multiple sclerosis, spina bifida, and diabetes. The needs of these populations are typically not discussed publicly by those afflicted and their caregivers and thus remain an unrecognized and underappreciated burden for them." He further emphasized; "Bladder and bowel dysfunction are top reasons for institutionalization of the elderly due to the heavy burdens associated with domestic caregiving. Similarly, restoration of bladder and bowel dysfunction in people with spinal injury is more important to them than restoration of their ability to walk." The new grants will allow Dignify to expand its therapeutic research and development efforts into providing innovative drug therapies for treating urinary and fecal incontinence, respectively. Similar to the unmet medical need for drugs to induce on-demand voiding in the elderly and people with neurological conditions, there is also a severe need in these same populations to prevent incontinence episodes. Dr. Qiaojuan Zhang, Principal Investigator on grant R43AG088838, will join Dignify from Duke University Department of Neurology to lead the NIA-sponsored research. About Dignify Therapeutics Founded by a team of serial entrepreneurs who are internationally recognized scientists and clinicians, Dignify's mission is to provide safe, effective, practical and convenient, "on-demand" pharmaceutical agents to treat bladder and bowel voiding dysfunctions. The company has been funded by RA Capital Management, Eshelman Ventures, the North Carolina Biotechnology Center, NIDDK, NINDS, NICHD, NIA, US Defense Department, and the One NC Small Business Program. Dignify is located at the First Flight Venture Center in Research Triangle Park, North Carolina. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. SOURCE Dignify Therapeutics WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED