Synonyms 4ガタコウシケッショウ, 4ガタコウシケツショウ, 4ガタコウリポタンパクケッショウ + [130] |
Introduction A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits. |
Target |
Mechanism Lipid modulators [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date10 Nov 2004 |
Target |
Mechanism HMG-CoA reductase inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. NL |
First Approval Date06 Nov 2002 |
Target |
Mechanism HMG-CoA reductase inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date17 Dec 1996 |
Start Date01 Jan 2025 |
Sponsor / Collaborator- |
Start Date13 Oct 2024 |
Sponsor / Collaborator- |
Start Date20 Sep 2024 |
Sponsor / Collaborator |