Last update 21 Mar 2024

Immunoglobulin Light-Chain Amyloidosis

Basic Info

Synonyms
AL, AL AMYLOIDOSIS, AL Amyloidoses
+ [43]
Introduction
A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.

Analysis

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