Last update 21 Mar 2024

Cold Agglutinin Disease

Basic Info

Synonyms
AIHA - Cold autoimmune haemolytic anaemia, AIHA - Cold autoimmune hemolytic anemia, AIHA-Cold autoim haemol anaem
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Introduction
Cold autoimmune hemolytic anemia comprises two types of autoimmune hemolytic anemia (AIHA; see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C): cold agglutinin disease (CAD), which is the more common, and paroxysmal cold hemoglobinuria (PCH; see these terms).

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