Last update 01 Nov 2024

Spider venom poisoning

Last update 01 Nov 2024

Basic Info

Synonyms

toxic reaction to venom of spider, toxic reaction to venom of spider (diagnosis)

Introduction-

Drugs associated with Spider venom poisoning

Latrodectus antivenin

Target-

Mechanism

Immunomodulators

Active Org.

Instituto Bioclon SA de CV

Originator Org.

Instituto Bioclon SA de CV

Active Indication

Spider venom poisoning [+1]

Inactive Indication

Pain [+1]

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date01 Jan 2014

Antivenin (Latrodectus mactans)(Merck Sharp & Dohme)

Target-

Mechanism

Immunomodulators

Active Org.

Merck Sharp & Dohme LLC

Originator Org.

Merck Sharp & Dohme LLC

Active Indication

Spider venom poisoning

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date13 Feb 1936

Clinical Trials associated with Spider venom poisoning

CTRI/2024/10/074872 / Not yet recruitingNot ApplicableIIT

A randomized controlled trial to evaluate the add on efficacy of Agastya lepa against Tambula hingu lepa in pitta kaphaja luta visa - NIL

Start Date15 Oct 2024

Sponsor / Collaborator-

RBR-7jz7hm / RecruitingPhase 3IIT

Effectiveness of the use of topical Tetracycline in cutaneous Loxoscelism - ETTCL: EFFECTIVENESS TOPICAL TETRACYCLINE CUTANEOUS LOXOSCELISM

Start Date01 Oct 2018

Sponsor / Collaborator-

100 Clinical Results associated with Spider venom poisoning

100 Translational Medicine associated with Spider venom poisoning

0 Patents (Medical) associated with Spider venom poisoning

Literatures (Medical) associated with Spider venom poisoning

01 Aug 2023·Journal of International Medical Research

Removal Notice

Review

Author: Alian, Shahriar ; Zakariaei, Ashkan ; Zakariaei, Zakaria ; Soleymani, Mostafa ; Fakhar, Mahdi ; Nourzad, Fatemeh

A brown recluse spider (BRS) bite is challenging to confirm, but may be clinically diagnosed by considering the location, the season of the year, and the clinical manifestations. Here, the case of a 26-year-old male who presented after an insect bite with a skin lesion, bruising, severe swelling, and diffuse blisters on the right lower extremity after three days, is described. Following clinical examination, patient history assessment, and consideration of other relevant factors, the patient received a differential diagnosis of necrotizing fasciitis caused by BRS bite. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, the outcomes may be devastating.

01 Jun 2023·Journal of surgical case reports

Massive dermal ulcerative lesions because of brown recluse spider bite: a rare case report and review of literature.

Author: Zakariaei, Ashkan ; Alian, Shahriar ; Zakariaei, Zakaria ; Nourzad, Fatemeh ; Fakhar, Mahdi

A brown recluse spider (BRS) bite is challenging to confirm, but can be clinically diagnosed by considering the location, the season of the year and the clinical manifestations. We described a 26-year-old male who presented after a BRS bite with a skin lesion, bruising, severe swelling and diffuse blisters on the right lower extremity after 3 days. This case should be considered in the differential diagnosis of necrotizing fasciitis. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, it can have devastating outcomes.

01 Nov 2022·BMJ Case Reports

Acute necrotic arachnidism with necrotising fasciitis and recurrent pneumothorax

Article

Author: Duggal, Jasleen ; Reddy, Shiva Kumar ; Rao, Swathi Sunil

A male infant presented with swelling of the left leg and fever. Over the next 2 days, the area developed fasciitis extending to the left thigh, abdomen, and lower chest. Meanwhile, the parents found a giant brown spider within the infant’s cot belonging to the genusLoxosceles, otherwise called the brown recluse spider. The dermo-myonecrosis progressed to deeper tissues involving the lung parenchyma requiring invasive ventilation. CT of the thorax showed multiple pneumatoceles, and lung biopsy showed alveolar necrosis. The infant was treated with intravenous antibiotics and corticosteroids. We drained the pneumothoraces by thoracostomy and insertion of intercostal drainage tubes. The infant required respiratory support initially by conventional ventilation, which was escalated to high-frequency oscillatory ventilation. He had refractory hypoxaemia and died. This is the first fatal case of acute spider envenomation described in India. Spider envenomation must be considered in patients with sudden onset, rapidly progressive necrotising fasciitis unresponsive to antibiotic therapy.

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Spider venom poisoning

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