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Last update 23 Jan 2025

Spider venom poisoning

Last update 23 Jan 2025

Basic Info

Synonyms

toxic reaction to venom of spider, toxic reaction to venom of spider (diagnosis)

Introduction-

Drugs associated with Spider venom poisoning

Latrodectus antivenin

Target-

Mechanism

Immunomodulators

Active Org.

Instituto Bioclon SA de CV

Originator Org.

Instituto Bioclon SA de CV

Active Indication

Spider venom poisoning [+1]

Inactive Indication

Pain [+1]

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date01 Jan 2014

Antivenin (Latrodectus mactans)(Merck Sharp & Dohme)

Target-

Mechanism

Immunomodulators

Active Org.

Merck Sharp & Dohme LLC

Originator Org.

Merck Sharp & Dohme LLC

Active Indication

Spider venom poisoning

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date13 Feb 1936

Clinical Trials associated with Spider venom poisoning

CTRI/2024/10/074872

/ Not yet recruitingNot ApplicableIIT

A randomized controlled trial to evaluate the add on efficacy of Agastya lepa against Tambula hingu lepa in pitta kaphaja luta visa - NIL

Start Date15 Oct 2024

Sponsor / Collaborator-

RBR-7jz7hm

/ RecruitingPhase 3IIT

Effectiveness of the use of topical Tetracycline in cutaneous Loxoscelism - ETTCL: EFFECTIVENESS TOPICAL TETRACYCLINE CUTANEOUS LOXOSCELISM

Start Date01 Oct 2018

Sponsor / Collaborator-

100 Clinical Results associated with Spider venom poisoning

100 Translational Medicine associated with Spider venom poisoning

0 Patents (Medical) associated with Spider venom poisoning

Literatures (Medical) associated with Spider venom poisoning

09 Nov 2024·Cureus

Black Widow Spider Envenomation and Cardiovascular Complications

Review

Author: Farina, Juan M ; Kapadia, Meera ; Khakh, Parmjot ; Aisenberg, Gabriel M ; Baranchuk, Adrian ; Lavercombe, William Q

Envenomation (latrodectism) with black widow spider (BWS) venom can cause dysfunction in the cardiovascular system. The pathophysiology and consequences of cardiovascular effects have not been fully elucidated. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Of 364 initial results, 22 articles (20 case reports and two case series) were used with 25 patients in total. Seventeen (68%) patients had hypertension, and 16 (64%) had tachycardia. High troponin levels were found in 16 (64%) patients. Electrocardiographic changes consisted of nine (36%) patients with ST-T segment abnormalities and three (12%) patients with supraventricular tachyarrhythmias. Wall motion abnormalities were present in 11 (44%) patients, with three of the patients experiencing left ventricle global hypokinesis. A reduced ejection fraction was present in 10 (40%) patients. Only six (24%) patients received antivenom and were discharged with no further complications. In conclusion, raising awareness for cardiovascular complications could be useful as there are no pathognomonic features in imaging or electrocardiogram (ECG). The impact of antivenom on cardiovascular complications has not been prospectively studied.

01 Aug 2023·Journal of International Medical Research

Removal Notice

Review

Author: Alian, Shahriar ; Zakariaei, Ashkan ; Zakariaei, Zakaria ; Soleymani, Mostafa ; Fakhar, Mahdi ; Nourzad, Fatemeh

A brown recluse spider (BRS) bite is challenging to confirm, but may be clinically diagnosed by considering the location, the season of the year, and the clinical manifestations. Here, the case of a 26-year-old male who presented after an insect bite with a skin lesion, bruising, severe swelling, and diffuse blisters on the right lower extremity after three days, is described. Following clinical examination, patient history assessment, and consideration of other relevant factors, the patient received a differential diagnosis of necrotizing fasciitis caused by BRS bite. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, the outcomes may be devastating.

01 Jun 2023·Journal of surgical case reports

Massive dermal ulcerative lesions because of brown recluse spider bite: a rare case report and review of literature.

Author: Zakariaei, Ashkan ; Alian, Shahriar ; Zakariaei, Zakaria ; Nourzad, Fatemeh ; Fakhar, Mahdi

A brown recluse spider (BRS) bite is challenging to confirm, but can be clinically diagnosed by considering the location, the season of the year and the clinical manifestations. We described a 26-year-old male who presented after a BRS bite with a skin lesion, bruising, severe swelling and diffuse blisters on the right lower extremity after 3 days. This case should be considered in the differential diagnosis of necrotizing fasciitis. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, it can have devastating outcomes.

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Spider venom poisoning

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