Last update 04 Nov 2024

Huperzine A

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HupA oral, Qian-ceng-ta, BIS-001
+ [6]
Mechanism
AChE inhibitors(Acetylcholinesterase inhibitors), NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
CN (01 Jan 1994),
RegulationOrphan Drug (US), Rare Pediatric Disease (US)
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Structure

Molecular FormulaC15H18N2O
InChIKeyZRJBHWIHUMBLCN-YQEJDHNASA-N
CAS Registry102518-79-6

External Link

KEGGWikiATCDrug Bank
-Huperzine A

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Alzheimer Disease
CN
01 Jan 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Drug Resistant EpilepsyPhase 2
AU
07 Feb 2023
SeizuresPhase 2
AU
07 Feb 2023
Epilepsies, PartialPhase 2
AU
10 Apr 2018
Brain Injuries, TraumaticPhase 2
US
01 Dec 2013
Cognitive DysfunctionPhase 2
US
01 Dec 2013
EpilepsyPhase 1
US
30 Jan 2022
Learning DisabilitiesPhase 1-17 Aug 2020
Learning DisabilitiesPhase 1-17 Aug 2020
Memory DisordersPhase 1-17 Aug 2020
Memory DisordersPhase 1-17 Aug 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
14
(Huperzine A)
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-
07 Oct 2019
Placebo
(Placebo)
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Regulation

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