Last update 07 Nov 2024

Nelotanserin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nelotanserin (USAN/INN), APD-125, RVT-102
Mechanism
5-HT2A receptor inverse agonists(Serotonin 2a (5-HT2a) receptor inverse agonists)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC18H15BrF2N4O2
InChIKeyCOSPVUFTLGQDQL-UHFFFAOYSA-N
CAS Registry839713-36-9

External Link

KEGGWikiATCDrug Bank
D09645Nelotanserin-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 2
US
01 Mar 2016
Dementia due to Parkinson's diseasePhase 2
US
01 Mar 2016
REM Sleep Behavior DisorderPhase 2
US
01 Mar 2016
HallucinationsPhase 2
US
01 Dec 2015
Lewy Body DiseasePhase 2
US
01 Dec 2015
Sleep Initiation and Maintenance DisordersPhase 2
US
01 Feb 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
34
(Nelotanserin)
emytpkvjjo(hmgcrasorj) = dvgrskvkzv caowbyrhsw (nwsdzegsne, zmentmycdz - rnjnzctscj)
-
20 May 2020
Placebo
(Placebo)
emytpkvjjo(hmgcrasorj) = vvdgnlbjmj caowbyrhsw (nwsdzegsne, ehwucgumzs - crvnstyoti)
Phase 2
-
-
aycrhbqglq(vyhfbvwsxu) = xfbosdnten fxgkqgybux (ogamovewok )
Positive
19 Jun 2016
aycrhbqglq(vyhfbvwsxu) = judkswjkpc fxgkqgybux (ogamovewok )
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Approval

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Regulation

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