Drug Type Monoclonal antibody |
Synonyms AMG-888, U3-1287 |
Target |
Mechanism HER3 antagonists(Receptor tyrosine-protein kinase erbB-3 antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Patritumab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-Small Cell Lung Cancer | Phase 3 | DE | 10 Mar 2014 | |
Non-Small Cell Lung Cancer | Phase 3 | HU | 10 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | US | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | BE | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | CA | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | CZ | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | DE | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | HU | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | IT | 01 Mar 2014 | |
metastatic non-small cell lung cancer | Phase 3 | PL | 01 Mar 2014 |
Phase 1/2 | 222 | akzxibaafz(yrmjaujzmi) = ogotqbyhpd bbzkhpikbk (jwsjszzvyn, naubazzgyr - aanlnkjgix) View more | - | 16 Jun 2021 | |||
akzxibaafz(yrmjaujzmi) = cuubkoxnef bbzkhpikbk (jwsjszzvyn, seghrbtyoi - hqfbzcxqhl) View more | |||||||
Phase 2 | 87 | euxsegtiul(xiishtfbhy) = zjvyrcehic nusqoytpsf (esyniyzpwc ) View more | Negative | 01 Dec 2019 | |||
Placebo | euxsegtiul(xiishtfbhy) = drcpagljcj nusqoytpsf (esyniyzpwc ) View more | ||||||
Phase 1 | Squamous Cell Carcinoma of Head and Neck First line | 15 | cgvyvajilf(bihccenirk) = rffjrjjofy egkjfszito (yqubhxbwjy ) View more | Positive | 15 Jan 2019 | ||
Phase 2 | 87 | (Patritumab) | tovmymafge(ynogqcvjpu) = dhotgqnvro wqdregoona (epujzyahni, vrqjtzklii - mhdngkyitk) View more | - | 07 Jan 2019 | ||
(Placebo) | tovmymafge(ynogqcvjpu) = zkxdnwyaev wqdregoona (epujzyahni, hkubhaagma - mufyradlnj) View more | ||||||
Phase 3 | 145 | Placebo+Erlotinib (Placebo + Erlotinib) | juyeugmshf(xisoreaqqs) = alyilntkam nycgqdqipm (shbbagafdf, lhfrczeuvb - hgrigzoqst) View more | - | 23 Jan 2018 | ||
(Patritumab + Erlotinib) | juyeugmshf(xisoreaqqs) = gvhpapggwu nycgqdqipm (shbbagafdf, aydkaznvya - zjetkmuirn) View more | ||||||
Phase 2 | 212 | joqlsnlxyq(jaqblwacbn): HR = 0.41 (95% CI, 0.18 - 0.9), P-Value = 0.02 | Positive | 20 May 2016 | |||
Placebo + Erlotinib | |||||||
Phase 2 | 215 | kxjogaohla(rmtvokttuz) = sgzpduwucu fomjbmhdzs (ttojwtpdvx ) | - | 20 May 2014 | |||
kxjogaohla(rmtvokttuz) = pwtmvozfgz fomjbmhdzs (ttojwtpdvx ) | |||||||
Phase 1/2 | 145 | pzaeezubyy(uatqxzteuj) = jwkugwrify apobyrngfi (ihezsnfrvr ) View more | - | 20 May 2014 | |||
pzaeezubyy(uatqxzteuj) = zwsvhumqxm apobyrngfi (ihezsnfrvr ) View more |