Last update 21 Jun 2024

GEN-1

Overview

Basic Info

Drug Type
Immune cell therapy
Synonyms
EGEN-001, IMNN-001, phIL-12-005/PPC
Target
Mechanism
IL-12R stimulants(Interleukin-12 receptor stimulants), Immunomodulators
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ovarian Epithelial CarcinomaPhase 2
US
05 Sep 2018
Ovarian Epithelial CarcinomaPhase 2
CA
05 Sep 2018
Primary peritoneal carcinomaPhase 2
US
05 Sep 2018
Primary peritoneal carcinomaPhase 2
CA
05 Sep 2018
Colorectal CancerPhase 2
US
01 Jun 2011
Fallopian Tube CarcinomaPhase 2
US
01 Nov 2010
Fallopian Tube CarcinomaPhase 2
US
01 Nov 2010
Platinum-Resistant Primary Peritoneal CarcinomaPhase 2
US
01 Nov 2010
Platinum-Resistant Primary Peritoneal CarcinomaPhase 2
US
01 Nov 2010
Recurrent ovarian cancerPhase 2
US
01 Nov 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
110
oalvzjxzir(whyjkjsgxf) = a delay in disease progression in the treatment arm of approximately 33% compared with the control arm gtoqaxwbap (cvlhvqcqaz )
Positive
28 Sep 2023
Phase 1
18
xbnlwlfuox(qbacwgpxpk) = OVATION-1 patients had more chills bacgvhtcok (umkajxidbh )
Positive
01 Jan 2023
Standard neoadjuvant chemotherapy
Phase 1
Ovarian Cancer
Neoadjuvant
18
Chemotherapy+GEN-1
xhajvhhbcu(tgcxiboxct) = tdfglyjrdh josrnuxrwr (jzcdywsppp )
Positive
15 Oct 2021
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Clinical Trial

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Approval

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Regulation

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