Zhejiang Hisun Pharmaceutical Co., Ltd.

NEW YORK, Nov. 9, 2023 /PRNewswire/ -- The Anti-CD20 monoclonal antibodies (maABs) market is expected to grow by USD 11.42 billion from 2023 to 2028. In addition, the momentum of the market will progress at a CAGR of 10.31% during the forecast period, according to Technavio Research. The market has been segmented by product (oncology, neurology, and immunology), type (first generation anti-CD20 monoclonal antibody, second generation anti-CD20 monoclonal antibody, and third generation anti-CD20 monoclonal antibody), and geography (North America, Europe, Asia, and Rest of World (ROW)). North America is estimated to contribute 57% to the growth of the global market during the forecast period. The growth of the market in North America is due to the high incidence and prevalence of hematological malignancies such as non-Hodgkin lymphoma (NHL). This report offers an up-to-date analysis of the current market scenario, the latest trends and drivers, and the overall market environment. Read PDF Sample Report Continue Reading Technavio has announced its latest market research report titled Global Anti-CD20 Monoclonal Antibodies (mABs) Market 2024-2028 Company Profile: Acrotech Biopharma Inc., Amgen Inc., AstraZeneca Plc, Celltrion Healthcare Co. Ltd., F. Hoffmann La Roche Ltd., Fosun International Ltd., Genmab AS, IGM Biosciences Inc., JSC BIOCAD, LFB SA, Novartis AG, Pfizer Inc., Regeneron Pharmaceuticals Inc., Spectrum Pharmaceuticals Inc., TG Therapeutics Inc., United BioPharma Inc., and ZHEJIANG HISUN PHARMACEUTICAL Co. Ltd. Amgen Inc. - The company offers anti-CD20 monoclonal antibodies such as Bax active monomer recombinant antibody 6A7 OAAV00544 and CD52 recombinant antibody campath 1H OAAV00552. To gain access to more company profiles available with Technavio, buy the report! Anti-CD20 Monoclonal Antibodies (mABs) Market: Segmentation Analysis The market share growth by the oncology segment will be significant during the forecast period. It is the availability of anti-CD20 mAbs in common cancer indications that has driven this segment's growth. Learn about the contribution of each segment summarized in concise infographics and thorough descriptions. View a PDF Sample Report "Besides analyzing the current market scenario, our report examines historic data from 2017 to 2021"- Technavio Anti-CD20 Monoclonal Antibodies (mABs) Market: Market Dynamics Increased use of combination therapies High target affinity and specificity of anti-CD20 mABs Strong pipeline and recent approvals Key Driver Increased use of combination therapies is a key factor driving market growth. In cases where the effectiveness and poor tolerability of monotherapy products are worse than in combination therapy, a combination treatment is usually preferable. In combination with other medicines to treat comorbid diseases, the market has seen a strong increase in the use of mABs against CD20. Major Trend The development of CD20 bispecific antibodies is the primary trend shaping market growth. Identify key trends, drivers, and challenges in the market. Download a sample to gain access to this information. Related Reports: The breast cancer monoclonal antibodies market size is estimated to grow by USD 15 billion at a CAGR of 12.5% between 2022 and 2027. The Biosimilars Market size is estimated to grow by USD 42.23 billion between 2022 and 2027, accelerating at a CAGR of 23% during the forecast period. What are the key data covered in this anti-CD20 monoclonal antibodies (mABs) market report? CAGR of the market during the forecast period Detailed information on factors that will drive the growth of the anti-CD20 monoclonal antibodies (mABs) market between 2023 and 2028. Precise estimation of the anti-CD20 monoclonal antibodies (mABs) market size and its contribution to the market in focus on the parent market Accurate predictions about upcoming trends and changes in consumer behavior Growth of the anti-CD20 monoclonal antibodies (mABs) market across North America, Europe, Asia, and ROW A thorough analysis of the market's competitive landscape and detailed information about companies Comprehensive analysis of factors that will challenge the growth of the anti-CD20 monoclonal antibodies (mABs) market companies. ToC: Executive Summary Market Landscape Market Sizing Historic Market Sizes Five Forces Analysis Market Segmentation by Product Market Segmentation by Type Market Segmentation by Geography Customer Landscape Geographic Landscape Drivers, Challenges, & Trends Company Landscape Company Analysis Appendix About Technavio Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provide actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contacts Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: SOURCE Technavio

JIAXING,China and BURLINGAME,Calif., Sept. 26, 2022 /PRNewswire/ -- Angel Pharmaceuticals Ltd. ("Angel Pharma"), a clinical-stage biopharmaceutical company, today announced that the IND application for mupadolimab (formerly CPI-006) has been approved by the Center for Drug Evaluation (CDE) to initiate a Phase 1/1b clinical trial in China. Angel Pharma owns mupadolimab's rights in Greater China. Mupadolimab is a humanized monoclonal antibody directed against CD73 . In preclinical studies, it has demonstrated immunomodulatory activity resulting in activation of lymphocytes, induction of antibody production from B cells and effects on lymphocyte trafficking. Compare with other anti-CD73 antibodies and smallmolecule drugs in development, mupadolimab is designed to react with a region of the molecule that acts to stimulate B cells and block production of immunosuppressive adenosine with a proposed unique mechanism of activating B cells to generate immune responses to tumor antigens and viruses. Outside China, mupadolimab has been studied in combination with pembrolizumab in a Phase 1/1b trial in patients with advanced head and neck cancers and in patients with NSCLC that have failed chemotherapy and anti-PD(L)1 therapy. Dr. Richard Miller, co-founder of Angel Pharmaceuticals, commented, "We are pleased that mupadolimab has been approved for clinical trial in China. Data from overseas clinical studies has demonstrated its safety and potential to benefit patients with advanced cancers. We look forward to working with clinical experts in China to accelerate its development." Dr. Ted Wang, Co-founder of Angel Pharmaceuticals, commented, "We have completed the local manufacture of mupadolimab in China, and will work closely with top clinical sites to bring it to market to benefit patients in China". Professor Guo Ye, Deputy Secretary General of the Chinese Clinical Oncology Society (CSCO), Chairman of the Head and Neck Cancer Committee of the Chinese Clinical Oncology Society, and Department of Oncology, Shanghai East Hospital Affiliated with Tongji University, commented, "CD73 plays a key role in the formation of the immunosuppressive microenvironment in cancer, and studies have demonstrated its importance on solid tumors. Mupadolimab is a unique CD73 antibody and we hope its clinical development will progress successfully in China to benefit cancer patients." About Angel Pharmaceuticals Angel Pharmaceuticals is a privately held biopharmaceutical company developing a pipeline of precisely targeted investigational medicines for cancer, autoimmune, infectious and other serious diseases. Angel Pharmaceuticals was launched with strategic collaboration with U.S. biopharmaceutical company Corvus Pharmaceuticals, Inc., with investments from Zhejiang Puissance Capital, Hisun Pharmaceuticals, Tigermed and fund associated with Betta Pharmaceuticals. For more information, visit www.angelpharma.com About Corvus Pharmaceuticals Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company. Corvus' lead product candidate is CPI-818, an investigational, oral, small molecule drug that selectively inhibited ITK in preclinical studies and is in a multicenter Phase 1/1b clinical trial in patients with several types of T-cell lymphomas. The Company's second clinical program, ciforadenant (CPI-444), is an oral, small molecule inhibitor of the A2A receptor. Its third clinical program, mupadolimab (CPI-006), is a humanized monoclonal antibody directed against CD73 that has exhibited immunomodulatory activity and activation of immune cells in preclinical and clinical studies. For more information, visit www.corvuspharma.com SOURCE Angel Pharmaceuticals

BURLINGAME, Calif., Sept. 26, 2022 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc (Corvus or the Company) (Nasdaq: CRVS), a clinical-stage biopharmaceutical company, today announced that the IND application to initiate a Phase 1/1b clinical trial of mupadolimab (formerly CPI-006) has been approved by the Center for Drug Evaluation of the China National Medical Products Administration. The study will be conducted by Angel Pharmaceuticals Ltd. (Angel Pharma), Corvus’ partner in China. Mupadolimab is a humanized monoclonal antibody designed to be directed against CD73 with a proposed unique mechanism of activating B cells to generate immune responses to tumor antigens and viruses, in patients with relapsed refractory non-small cell lung cancer (NSCLC) and head and neck squamous cell cancers (HNSCC). Corvus co-founded Angel Pharma to develop its pipeline in greater China. Angel Pharma licensed the rights from Corvus to develop, manufacture and commercialize mupadolimab in greater China. Corvus has studied mupadolimab in a Phase 1/1b clinical trial, with a focus on expansion cohorts in patients with (1) HNSCC that have failed previous treatment with anti-PD-1 therapy and chemotherapy and (2) relapsed refractory NSCLC who have failed previous treatment with anti-PD(L)-1 therapy and chemotherapy. Based on the results to-date, Corvus believes this program is ready to advance into a randomized Phase 2 clinical trial evaluating mupadolimab in combination with pembrolizumab and chemotherapy as a potential front-line therapy for the treatment of patients with NSCLC. “Our partnership with Angel Pharma continues to support the efficient development of our pipeline,” said Richard A. Miller, M.D., co-founder, president and chief executive officer of Corvus. “In our development work, we have characterized mupadolimab’s unique potential as an anti-CD73 antibody that blocks adenosine production and activates the immune system. Angel Pharma’s development strategy is consistent and supportive of our studies, with the potential to further expand mupadolimab’s opportunity in China and globally. They are continuing the development and clinical testing in patients with NSCLC and head and neck cancer.” Angel Pharma is examining mupadolimab in a Phase 1/1b clinical trial designed to confirm the dose and evaluate the safety, pharmacokinetics, immune biomarkers, and efficacy as a single agent, and in combination with pembrolizumab. Patients with NSCLC and HNSCC are eligible. The clinical trial’s efficacy endpoints are complete response, partial response, disease control rate, duration of response, progression-free survival, and overall survival. About Angel Pharmaceuticals Angel Pharma is a privately held biopharmaceutical company developing a pipeline of precisely targeted investigational medicines for cancer, autoimmune, infectious and other serious diseases in China. Angel Pharma was launched through strategic collaboration with U.S.-based Corvus Pharmaceuticals and investments from Zhejiang Puissance Capital, Hisun Pharmaceuticals, Tigermed and funds associated with Betta Pharmaceuticals. Corvus owns a 49.7% equity stake in Angel. For more information, visit . About Corvus Pharmaceuticals Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company. Corvus’ lead product candidate is CPI-818, an investigational, oral, small molecule drug that selectively inhibited ITK in preclinical studies and is in a multicenter Phase 1/1b clinical trial in patients with several types of T-cell lymphomas. The Company’s second clinical program, ciforadenant (CPI-444), is an oral, small molecule inhibitor of the A2A receptor. Its third clinical program, mupadolimab (CPI-006), is a humanized monoclonal antibody directed against CD73 that has exhibited immunomodulatory activity and activation of immune cells in preclinical and clinical studies. For more information, visit . About Mupadolimab Mupadolimab (CPI-006) is an investigational, potent humanized monoclonal antibody that is designed to react with a specific site on CD73. In preclinical studies, it has demonstrated immunomodulatory activity resulting in activation of lymphocytes, induction of antibody production from B cells and effects on lymphocyte trafficking. While there are other anti-CD73 antibodies and small molecules in development for treatment of cancer, such agents react with a different region of CD73. Mupadolimab is designed to react with a region of the molecule that acts to stimulate B cells and block production of immunosuppressive adenosine. Mupadolimab has been studied in combination with pembrolizumab in a Phase 1b/2 clinical trial in patients with advanced HNSCC and in patients with NSCLC that have failed chemotherapy and anti-PD(L)1 therapy. It is postulated that the activation of B cells will enhance immunity within the tumors of these patients, leading to improved clinical outcomes. Forward-Looking Statements This press release contains forward-looking statements, including statements related to the potential safety and efficacy of CPI-818, mupadolimab and ciforadenant; the Company’s ability and Angel Pharma’s ability, as well as the timing thereof, to develop and advance product candidates into and successfully complete preclinical studies and clinical trials, including Angel Pharma’s planned Phase 1/1b clinical trial of mupadolimab; and the expected trial design of the Company and Angel Pharma’s upcoming planned clinical trials. All statements other than statements of historical fact contained in this press release are forward-looking statements. These statements often include words such as “believe,” “expect,” “anticipate,” “intend,” “plan,” “estimate,” “seek,” “will,” “may” or similar expressions. Forward-looking statements are subject to a number of risks and uncertainties, many of which involve factors or circumstances that are beyond the Company or Angel Pharma’s control. The Company and Angel Pharma’s actual results could differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to, risks detailed in the Company’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2022, filed with the Securities and Exchange Commission on August 8, 2022, as well as other documents that may be filed by the Company from time to time with the Securities and Exchange Commission. Although the Company believes that the expectations reflected in the forward-looking statements are reasonable, it cannot guarantee that the events and circumstances reflected in the forward-looking statements will be achieved or occur, and the timing of events and circumstances and actual results could differ materially from those projected in the forward-looking statements. Accordingly, you should not place undue reliance on these forward-looking statements. All such statements speak only as of the date made, and the Company undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise. INVESTOR CONTACT: Leiv Lea Chief Financial Officer Corvus Pharmaceuticals, Inc. +1-650-900-4522 llea@corvuspharma.com MEDIA CONTACT: Aulani Capuchin Real Chemistry +1-559-355-2673 acapuchin@realchemistry.com