Last update 24 May 2025

Trafermin

Overview

Basic Info

Drug Type
Growth factors
Synonyms
bFGF, Fiblast Spray, REGROTH Dental Kit
+ [11]
Target
Action
stimulants
Mechanism
FGFRs stimulants(Fibroblast growth factor receptors stimulants)
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (04 Apr 2001),
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D03362Trafermin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Periodontitis
Japan
28 Sep 2016
Pressure Ulcer
Japan
04 Apr 2001
Skin Ulcer
Japan
04 Apr 2001
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic foot ulcerPhase 3
Czechia
01 Nov 2010
Diabetic foot ulcerPhase 3
France
01 Nov 2010
Diabetic foot ulcerPhase 3
Hungary
01 Nov 2010
Diabetic foot ulcerPhase 3
Italy
01 Nov 2010
Alveolar Bone LossPhase 3
Japan
01 Aug 2008
Periodontal Attachment LossPhase 3
Japan
01 Aug 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
201
(Trafermin 0.01% Spray)
ixcirigldw = qlwqjdcjgd pukrsuostn (zakohaonyy, zazxtlvnaz - gfygkukegl)
-
05 Aug 2014
(Matching Placebo Spray)
ixcirigldw = xdrwpqzuyy pukrsuostn (zakohaonyy, xhepfshadb - ctrywkgyoc)
Phase 3
207
(Trafermin)
voxhyobxhg = kiugpotwhs kjihgijlfy (pofolhixnp, wulmfacome - orwokostbp)
-
05 Aug 2014
placebo
(Placebo)
voxhyobxhg = uhmxfavivw kjihgijlfy (pofolhixnp, cntnogmqqs - gkvrmdxake)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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