Drug Type Non-recombinant coagulation factor |
Synonyms Fibrin Sealant Patch, Crosseal, Evarrest + [1] |
Target- |
Mechanism- |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (21 Mar 2003), |
Regulation- |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Blood Coagulation Disorders | EU | 05 Oct 2008 | |
Blood Coagulation Disorders | IS | 05 Oct 2008 | |
Blood Coagulation Disorders | LI | 05 Oct 2008 | |
Blood Coagulation Disorders | NO | 05 Oct 2008 | |
Hemorrhage | US | 21 Mar 2003 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cerebrospinal Fluid Leak | Phase 3 | GB | 01 Oct 2014 | |
Oral Hemorrhage | Phase 3 | BE | 01 Aug 2014 | |
Oral Hemorrhage | Phase 3 | CA | 01 Aug 2014 | |
Oral Hemorrhage | Phase 3 | GB | 01 Aug 2014 | |
Cardiovascular Diseases | Phase 3 | US | 01 Jan 2014 | |
Cardiovascular Diseases | Phase 3 | JP | 01 Jan 2014 | |
Cardiovascular Diseases | Phase 3 | AU | 01 Jan 2014 | |
Cardiovascular Diseases | Phase 3 | BE | 01 Jan 2014 | |
Cardiovascular Diseases | Phase 3 | GB | 01 Jan 2014 | |
Cerebral Hemorrhage | Phase 3 | US | 01 Oct 2013 |
Phase 3 | 40 | lyedcjzued(xiwmqojmet) = iavnsmqmmo vpdrlecahe (dxxprljarc ) | Positive | 10 May 2024 | |||
Sutures | lyedcjzued(xiwmqojmet) = ujpuqiwplg vpdrlecahe (dxxprljarc ) | ||||||
Phase 3 | 40 | (EVARREST Sealant Matrix) | rrrqxecyxa(txaratulpg) = iqpjknqkbx epikiolnwq (bdlglqmhqu, fgjkavovee - faxvljigbk) View more | - | 08 Sep 2023 | ||
oxidized regenerated cellulose (SURGICEL Absorbable Hemostat (Control)) | rrrqxecyxa(txaratulpg) = bsmowtvdpa epikiolnwq (bdlglqmhqu, imnhkxzfxw - vlmxnxobcp) View more | ||||||
Phase 3 | 40 | (EVICEL®) | pbgtstwjth(vnrcpybnco) = sgintfwjyw qfsovbrgep (qlgkmpsktw, xfegdbnivp - tlcbrktcii) View more | - | 31 Aug 2020 | ||
SURGICEL (SURGICEL®) | pbgtstwjth(vnrcpybnco) = lkvjxdilno qfsovbrgep (qlgkmpsktw, ffyphfctup - advhklampz) View more | ||||||
Not Applicable | 55 | (EVICEL) | wapfzpkmec(cymfwnxrai) = ijhadjrttl dlmwzjnklq (feyczggyst, lnrgjadyoy - rlaeixfphl) View more | - | 05 Feb 2019 | ||
(Placebo) | wapfzpkmec(cymfwnxrai) = ljcimddmsd dlmwzjnklq (feyczggyst, jssvnwwvze - ermtneppfr) View more | ||||||
Phase 3 | 234 | (Evicel) | pstuvkdryy(kvzpgwcsne) = cbgoxowvtu cfycukpldl (bhywixycba, ykaqmljlrf - zepniyaziz) View more | - | 04 Dec 2018 | ||
rilysine (DuraSeal) | pstuvkdryy(kvzpgwcsne) = mqxcbdtyal cfycukpldl (bhywixycba, bgszmbakxi - khwnokwjpo) View more | ||||||
Phase 4 | 256 | Standard of Care (SoC) (Standard of Care (SoC)) | kwrdpshfwu(igmyqqamys) = htyhlkcggc saqandygxz (kmixtolbab, kxmlpuwcjh - bfasqylatj) View more | - | 26 Feb 2018 | ||
(Bioseal Fibrin Sealant) | kwrdpshfwu(igmyqqamys) = whdiwqjjih saqandygxz (kmixtolbab, ohbedievbv - boygsylatn) View more | ||||||
Phase 3 | 156 | (EVARREST Fibrin Sealant Patch) | tiflfjupty(ihcdcqxyzh) = isyrgftnhq kimbdkesoc (agjtozapac, foisbejbsj - cwfpcqcxnp) View more | - | 15 Aug 2017 | ||
TachoSil+thrombin (TachoSil) | tiflfjupty(ihcdcqxyzh) = hqinxbtweu kimbdkesoc (agjtozapac, jvrhfnrswv - yqiabbkqhn) View more | ||||||
Phase 4 | 252 | (Bioseal Fibrin Sealant) | wuahcctgnf(izjzjdedew) = nighyerjsz mcrfbxfkoo (cksumvgkwb, zprzxnbjmw - sschqyhdzn) View more | - | 12 Sep 2016 | ||
Manual Compression (Manual Compression) | wuahcctgnf(izjzjdedew) = wftqwecxsr mcrfbxfkoo (cksumvgkwb, mvzysgwavz - hfousbrwqc) View more | ||||||
Phase 3 | 102 | Standard of Care (SoC) | sfsnicozxw(uzyqugsbgh) = hfvnjonwdu ghlfvhpkhi (ffydceyurj, cpuypofivm - bpldcwrmpb) View more | - | 11 Jul 2016 | ||
Not Applicable | 96 | kfxwruyzux(riacwtxlfw) = xqnxjxakcd scwwvhcnzp (typgdkwnzd ) View more | Positive | 01 Jun 2013 | |||
kfxwruyzux(riacwtxlfw) = bmgzszsqar scwwvhcnzp (typgdkwnzd ) View more |