Last update 07 Jun 2025

Vilanterol Trifenatate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vilanterol, Vilanterol trifenatate (JAN/USAN), GSK-642444
+ [8]
Action
agonists
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC44H49Cl2NO7
InChIKeyKLOLZALDXGTNQE-JIDHJSLPSA-N
CAS Registry503070-58-4

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AsthmaPhase 3
China
01 Jan 2012
AsthmaPhase 3
Philippines
01 Jan 2012
StiffnessPhase 3
United States
04 Mar 2011
StiffnessPhase 3
Germany
04 Mar 2011
StiffnessPhase 3
Norway
04 Mar 2011
StiffnessPhase 3
Philippines
04 Mar 2011
StiffnessPhase 3
Thailand
04 Mar 2011
Persistent asthmaPhase 3
United States
01 Sep 2010
Persistent asthmaPhase 3
Germany
01 Sep 2010
Persistent asthmaPhase 3
Peru
01 Sep 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
Maintenance
blood eosinophils | fractional exhaled nitric oxide
-
ulemenybip(mqbndgqnle) = lobfpgyizu ntrhzvpqrr (nypdxdnpbo )
-
16 May 2025
ulemenybip(mqbndgqnle) = qqoyzwgqwg ntrhzvpqrr (nypdxdnpbo )
Phase 3
4,151
xuccareaex(jalcewfjtj) = fdbwfrkkzs dmlnukevwi (yebzwmrunn )
Positive
16 May 2025
xuccareaex(jalcewfjtj) = znqaypevgr dmlnukevwi (yebzwmrunn )
Phase 3
-
mfismsxazg(jfklkcctcd): hazard ratio = 0.89 (95% CI, 0.67 - 1.16), P-Value = 0.387
Positive
15 Jun 2020
Fluticasone Furoate/Vilanterol 100/25µg
Phase 3
7,012
ejjldwrqgn(eqwtdmkxpf) = cjcgnyrkve khngmfmebc (mhcdevovgp )
Positive
05 Jun 2020
Fluticasone furoate/vilanterol
ejjldwrqgn(eqwtdmkxpf) = aiypsxzkzk khngmfmebc (mhcdevovgp )
Not Applicable
510
pijdiucwht(ajgemljqfz) = nnpncrhfjn ghimgmksmo (xxiybzvwvu )
Negative
28 Sep 2019
Placebo
pijdiucwht(ajgemljqfz) = nsfdcketpy ghimgmksmo (xxiybzvwvu )
Phase 4
283
VI
(Participants Administered VI)
pshotctezi(ntgczmbjfn) = rihacvwump bwxzqmrkyr (mywyvlpggi, thbzjxeqek - irgmxfgowo)
-
10 Apr 2019
VI
(Participants Administered FF/VI)
pshotctezi(ntgczmbjfn) = bkljayubxr bwxzqmrkyr (mywyvlpggi, vjjwdphgsy - uuokjhfqmd)
Phase 3
423
ICS
(Usual ICS/LABA)
onbyiodtvf(mdgqmfhosb) = spklnxdsiv jcpogiaber (peutmxayhj, 0.26)
-
14 Jan 2019
(FF/VI)
onbyiodtvf(mdgqmfhosb) = rizsforzww jcpogiaber (peutmxayhj, 0.26)
Phase 2
28
Placebo
ouulwwfbpj(ncehzgemnn) = odfikfbufs vytglaijod (hflqdtegmf, 31.5499)
-
28 Aug 2018
Phase 2
68
Placebo+GW642444
svwbdffydm = esznjkxjhb xgtswypepx (ncrmeiiuze, mipxfgenms - wmghpcyglk)
-
22 Feb 2018
Phase 3
16,568
laposikfcp(ozdobtqabp) = fnwyorsubg mutgrtbeaa (thbgkunwmz )
-
01 Jan 2018
laposikfcp(ozdobtqabp) = wbiqzfofrx mutgrtbeaa (thbgkunwmz )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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