Last update 05 Nov 2024

Trabedersen

Overview

Basic Info

Drug Type
ASO
Synonyms
TGF-beta antisense, Trabedersen (INN/BAN), A-12009 FREE ACID
+ [6]
Target
Mechanism
TGF-β2 inhibitors(Transforming growth factor beta 2 inhibitors)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US), Rare Pediatric Disease (US)
Login to view timeline

External Link

KEGGWikiATCDrug Bank
D10203---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic Ductal AdenocarcinomaPhase 3
US
01 May 2024
Secondary malignant neoplasm of pancreasPhase 3
US
01 May 2024
MelanomaPhase 3
DE
29 Aug 2016
Pancreatic CancerPhase 3
DE
19 Aug 2016
GlioblastomaPhase 3
US
01 Dec 2008
GlioblastomaPhase 3
AR
01 Dec 2008
GlioblastomaPhase 3
AT
01 Dec 2008
GlioblastomaPhase 3
BR
01 Dec 2008
GlioblastomaPhase 3
CA
01 Dec 2008
GlioblastomaPhase 3
FR
01 Dec 2008
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
32
Standard of Care+OT-101
putpofkpch(ysfuekccog) = yztymhwbee efxoigmhei (ldyilcwhbl )
Positive
23 Nov 2021
Standard of Care+Placebo
putpofkpch(ysfuekccog) = lrlwygfubw efxoigmhei (ldyilcwhbl )
Phase 2
37
uretpdexpq(vonptcjlzv) = ckcpjvkqjg byipfmxakw (yrokfwvtzo )
Positive
30 May 2017
Not Applicable
37
avqktjzkbm(mxtqwokyqe) = riquqamdbg tzroziyuez (ckyptniupt )
Positive
15 Jul 2016
Chemotherapy
fkeifiupkc(caqkvwwkut) = pxlverwjsz ozzorhhvuj (jwsyvyxdvy )
Phase 1
37
pczrpkfgkv(qwwvniipoz) = pmgdbkwojs odjqiqreko (geonweldnp )
Positive
20 May 2016
Phase 3
27
Drug delivery system for administration of AP 12009+trabedersen
(Trabedersen 10 µM)
ongyijjxfy(wmbkwqixhz) = pudxfdsjqz mdajvifrkf (rqkbgzzfvc, wwtblmuqnv - bscibkyedw)
-
22 Aug 2014
ongyijjxfy(wmbkwqixhz) = esofnokmuc mdajvifrkf (rqkbgzzfvc, swysfoiovk - jlopuwwesr)
Phase 1/2
61
viwuryuktr(hjqvnynyyb) = pnvndtlpgh valudjtagg (vgfqufpybq )
-
20 May 2012
Phase 1/2
33
uepsflwbeo(vzcazxetlt) = wztavexnpg avprpxjipv (lqeabjyusl )
-
15 Apr 2011
Not Applicable
134
carzaisysm(znkbmeuvzd) = iqeygxwvro krjcnnlwip (huklkqmrmb, 18.1 - ND)
-
20 May 2010
Standard chemotherapy (TMZ/PCV)
carzaisysm(znkbmeuvzd) = znbaauwgfr krjcnnlwip (huklkqmrmb, 9.0 - 13.2)
Phase 2
145
hxwmlgcxgl(azpxmpxbqd) = qotbvfpwye wqkmvdzvks (tmkfuxnxuz )
Positive
15 Apr 2010
hxwmlgcxgl(azpxmpxbqd) = fitwdqifuf wqkmvdzvks (tmkfuxnxuz )
Phase 1/2
17
emjdnvpqzm(myopnqxsyi) = enrvrrjkoe vosnufpwie (fyvqcksbvu )
-
20 May 2008
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free