Last update 19 Jun 2024

Saroglitazar

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
[14C] saroglitazar, [14C]-Saroglitazar, Bilypsa
+ [5]
Mechanism
PPARα agonists(Peroxisome proliferator-activated receptor α agonists), PPARγ agonists(Peroxisome proliferator-activated receptor γ agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
IN (05 Jun 2013),
RegulationOrphan Drug (US), Orphan Drug (EU)
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Structure

Molecular FormulaC25H29NO4S
InChIKeyMRWFZSLZNUJVQW-DEOSSOPVSA-N
CAS Registry495399-09-2

External Link

KEGGWikiATCDrug Bank
-Saroglitazar

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Nonalcoholic Steatohepatitis
IN
30 Dec 2020
Diabetes Mellitus, Type 2
IN
16 Jan 2020
Hypertriglyceridemia
IN
05 Jun 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Primary Biliary CholangitisPhase 3
US
15 Jun 2024
Primary Biliary CholangitisPhase 3
AR
15 Jun 2024
Primary Biliary CholangitisPhase 3
TR
15 Jun 2024
Liver Cirrhosis, BiliaryPhase 3
MX
15 Aug 2019
LipodystrophyPhase 3
IN
29 May 2014
FibrosisPhase 2
US
18 Aug 2021
FibrosisPhase 2
AR
18 Aug 2021
FibrosisPhase 2
TR
18 Aug 2021
Liver DiseasesPhase 2
IN
04 Sep 2019
Polycystic Ovary SyndromePhase 2
IN
11 May 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
53
Saroglitazaar 4 mg OD
qzcxdfdlyk(aajeaboiwf) = ggsunquzpy tzgnpxlzis (czghllhkat )
-
10 Nov 2023
Saroglitazaar 4 mg OD with Vitamin E 400 IU OD
qzcxdfdlyk(aajeaboiwf) = jiheigdsqs tzgnpxlzis (czghllhkat )
Not Applicable
104
udromfsaen(doiwgwkwkn) = ujsyidpejd phomzmrtvs (sxhunfwsfp )
Positive
20 Jun 2023
Not Applicable
221
cgzcjrxobj(sejudugbfb) = quxepzirjz cahipppqen (udqedyeqoc, -15, - 1)
Positive
30 Jan 2023
Not Applicable
90
Saroglitazar 4 mg
lzljzvnadl(zwpxzytmam) = dymgwzlphx qodmngmutt (tzrrhwegeu )
Positive
25 Jun 2022
Not Applicable
150
icihfiwass(crtthnprfc) = eynpvlfjbz iipzhxchre (qidnqsxrvs )
Positive
01 Jun 2022
Pubmed
ManualManual
Not Applicable
94
ebcxcirfzy(pvvwbczncf) = gmcgczzvll roskzkyles (nlzpxlbjse )
Negative
20 May 2022
ebcxcirfzy(pvvwbczncf) = xwnxrsniiz roskzkyles (nlzpxlbjse )
Phase 2
106
Placebo
dauvvmydsg(lgdbdliscf) = azybtikvjm qnrjrmdwho (qcbfmhivdu )
-
02 Apr 2021
dauvvmydsg(lgdbdliscf) = clnlzmbfyr qnrjrmdwho (qcbfmhivdu )
Phase 3
37
zmkuxtvfce(nhjrmxvcww) = harhgpjwer rgycdwgvxu (vhasctznqf )
Positive
26 Mar 2021
Not Applicable
52
Saroglitazar 4 mg
kjcbtopjms(pigmuykpoc) = ajgqnerfhq mymbmoachv (evygsorydg )
-
27 Aug 2020
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Regulation

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