Last update 12 Dec 2024

Padnarsertib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ATG 019, ATG-019, KCP-9274
+ [1]
Mechanism
NAMPT inhibitors(Nicotinamide phosphoribosyltransferase inhibitors), PAK4 inhibitors(Serine/threonine-protein kinase PAK 4 inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC35H29F3N4O3
InChIKeyMRFOPLWJZULAQD-SWGQDTFXSA-N
CAS Registry1643913-93-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 2-22 Jun 2022
Refractory acute myeloid leukemiaPhase 1
US
27 Aug 2021
Relapsing acute myeloid leukemiaPhase 1
US
27 Aug 2021
Advanced Malignant Solid NeoplasmPhase 1
US
08 Jun 2016
Advanced Malignant Solid NeoplasmPhase 1
CA
08 Jun 2016
Non-Hodgkin LymphomaPhase 1
US
08 Jun 2016
Non-Hodgkin LymphomaPhase 1
CA
08 Jun 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Core Patent

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Clinical Trial

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Approval

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Regulation

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