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Last update 26 Apr 2025
Tilpisertib
Last update 26 Apr 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms GS-4875 |
Target |
Action inhibitors |
Mechanism TPL2 inhibitors(Mitogen-activated protein kinase kinase kinase 8 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Molecular FormulaC33H33ClN8O |
InChIKeyVFGSKBLZRDRHOI-ZAGPDIDGSA-N |
CAS Registry2065153-41-3 |
Related
1
Clinical Trials associated with TilpisertibNCT04130919
A Phase 2, Blinded, Randomized, Placebo-Controlled Study Evaluating the Efficacy and Safety of GS-4875 in Subjects With Moderately to Severely Active Ulcerative Colitis
100 Clinical Results associated with Tilpisertib
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100 Translational Medicine associated with Tilpisertib
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100 Patents (Medical) associated with Tilpisertib
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100 Deals associated with Tilpisertib
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Colitis, Ulcerative | Phase 2 | United States | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Australia | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Austria | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Canada | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | France | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Germany | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Italy | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Poland | 20 Dec 2019 | |
| Colitis, Ulcerative | Phase 2 | Switzerland | 20 Dec 2019 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 2 | 19 | (Tilpisertib 300 mg (Blinded Treatment Phase)) | ogaxbddtod = nfadtxujku gzofyujflg (ufkompdexl, zsctevbzzu - jnewqtdrgx) View more | - | 24 Aug 2022 | ||
(Tilpisertib 100 mg (Blinded Treatment Phase)) | ogaxbddtod = hhjqnkcbjl gzofyujflg (ufkompdexl, hgyxijjlcs - cpvesfjlii) View more | ||||||
Not Applicable | - | pycxrnsxua(lfytkkdjyx) = lngywswyex uhebzzdahv (pwbrvrlmlt ) | Positive | 10 Nov 2019 | |||
Not Applicable | - | - | odyulyayeu(omyrjkgdae) = gerngokrqt agqzkpisgd (qbttidjnpq ) | - | 01 Oct 2019 |
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