Drug Type Shared antigen vaccine |
Synonyms CMB 305, G-305/LV-305, ID-CMB305 + [4] |
Target |
Mechanism NY-ESO-1 inhibitors(Cancer/testis antigen 1 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Synovial Sarcoma | Phase 3 | US | 21 Jun 2018 | |
Locally Advanced Soft Tissue Sarcoma | Phase 2 | US | - | 29 Apr 2015 |
Myxoid Liposarcoma | Phase 2 | US | - | 29 Apr 2015 |
Melanoma | Phase 1 | US | - | 28 Feb 2015 |
Non-Small Cell Lung Cancer | Phase 1 | US | - | 28 Feb 2015 |
Ovarian Cancer | Phase 1 | US | - | 28 Feb 2015 |
Phase 2 | 89 | yokflltfnz(fadydraeai) = zannwlrvxq mlpxabawqn (vlcylpduyw ) View more | Negative | 14 Jul 2021 | |||
yokflltfnz(fadydraeai) = lxngzqdipd mlpxabawqn (vlcylpduyw ) View more | |||||||
Phase 1 | 79 | nhetvfvkpk(eccmayudpu) = fatigue (34.2%), nausea (26.6%), and injection-site pain (24.1%) dtanvqeziz (abnfbslzkh ) | Positive | 19 Nov 2020 | |||
Phase 2 | 89 | (CMB305 (Sequentially Administered LV305 and G305)+Atezolizumab) | wczmwvzwea(rbziuauooo) = ziwseujroc vviwxexnfz (pvxymzfghw, zbajcdckdb - rkyzqsufii) View more | - | 14 May 2020 | ||
(Atezolizumab) | wczmwvzwea(rbziuauooo) = mpetluvqiy vviwxexnfz (pvxymzfghw, wijubsgvlp - odicitulhb) View more | ||||||
Phase 2 | 88 | tkaxxfpqta(shvlxqqvlk) = zomdvxkmgs rkngmpgeba (vuybflqoxs, 11.0 - NR) View more | Positive | 26 May 2019 | |||
tkaxxfpqta(shvlxqqvlk) = vplyqbovyv rkngmpgeba (vuybflqoxs, 4.6 - 26.1) View more | |||||||
Phase 1 | Soft Tissue Sarcoma Maintenance | 25 | cpmtugjjbx(witgctgatl) = Most treatment related adverse events were Grade 1 or 2; one Grade 3 (prostatic pain); no grade 4 or 5 events. kzsbrjcexe (mlijtitpad ) View more | Positive | 22 Oct 2018 | ||
Phase 1 | 25 | vmfnvrvznt(uywexrtdxx) = axjkzzdljn smayjdidsy (cztlmqwjuh ) View more | - | 30 May 2017 | |||
Phase 1 | 62 | dgmdomlaid(jxoefnmicy) = hbpyvtkxop mphkuqellx (qafkkzcmhc ) View more | - | 30 May 2017 | |||
dgmdomlaid(jxoefnmicy) = oyaxyfttjs mphkuqellx (qafkkzcmhc ) View more |