Last update 16 May 2024

XTX-101

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
Mechanism
CTLA4 inhibitors(Cytotoxic T-Lymphocyte-Associated Antigen 4 inhibitors)
Therapeutic Areas
Inactive Indication-
Originator Organization
Active Organization
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
US
13 Sep 2021
Solid tumorDiscovery
US
13 Sep 2021
Solid tumorDiscovery
US
13 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
22
(ucwjhjzbuf) = 1 dose limiting toxicity (DLT) of colitis among 8 patients treated at 60 mg Q3W, while 2 DLTs of colitis were reported among 6 pts at 180 mg Q3W. kklitptoef (zoohbijnqo )
Positive
26 May 2023
Phase 1
18
XTX101 150mg
(qnwhpvcoqu) = epdbqmtzbi ayowfhxnxk (kxygdzaddp )
Positive
07 Dec 2023
Phase 1/2
12
(ekaphswerx) = A maximum tolerated dose (MTD) has not yet been determined, and enrollment in the dose-escalation cohort is ongoing. xaywxmcxyi (xdolpqufho )
Positive
09 Aug 2022
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Clinical Trial

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Approval

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Regulation

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