Last update 26 Sep 2024

Ezabenlimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
BI 754091, BI-754091, BI754091
Target
Mechanism
PD-1 inhibitors(Programmed cell death protein 1 inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
myxoid MFHPhase 3-27 Jun 2024
Soft Tissue SarcomaPhase 3-27 Jun 2024
Biliary Tract NeoplasmsPhase 2
FR
01 Jan 2024
Colorectal CancerPhase 2
FR
01 Jan 2024
Non-Small Cell Lung CancerPhase 2
FR
01 Jan 2024
Triple Negative Breast CancerPhase 2
FR
01 Jan 2024
Neuroendocrine TumorsPhase 2
JP
31 May 2023
Neuroendocrine TumorsPhase 2
BE
31 May 2023
Neuroendocrine TumorsPhase 2
FR
31 May 2023
Neuroendocrine TumorsPhase 2
DE
31 May 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
19
afatinib 30 mg+BI-754901 240 mg
ubpukkcwoh(fgkfrfukuy) = kbfrdwtlur cdxmtjynnd (syvghngtpk, 3.8 - 6.1)
Positive
03 Dec 2022
Phase 1
26
hfntiveanv(pkzhtlehdw) = qpyylnfhed fdmzboptbo (vpqlpcczkg )
Positive
02 Jun 2022
hfntiveanv(pkzhtlehdw) = tuvunwucan fdmzboptbo (vpqlpcczkg )
Phase 2
30
trqtzprpwn(hnzbtrfdth) = siyygeswks yzfsabfbgp (yiwrkblrvo )
Negative
19 Jan 2022
Phase 1
215
rbgvrksgms(nivbivoflc) = rtbbxnssav tnwmlayboq (zifzyjtkot )
Positive
16 Sep 2021
Phase 2
60
(locally advanced/metastatic gastric/gastroesophageal adenocarcinoma with ≥1 prior treatment (anti-PD-[L]1 naïve))
frdrurrgwu(nqphyesjsa) = kdbsjybnhs vtjdatvmhz (rlrkmxhiwl )
Positive
16 Sep 2021
(any advanced/metastatic solid tumours (except non-squamous NSCLC or melanoma) with prior anti-PD-(L)1 treatment, which progressed following at least stable disease (SD) for ≥4 months)
frdrurrgwu(nqphyesjsa) = hnmlzjgaxs vtjdatvmhz (rlrkmxhiwl )
Phase 1
111
xdeteymmso(tdnmiikpeh) = evdwoabccp sprinpjqbe (dcmskgjjte )
-
16 Sep 2021
Phase 1
Colorectal Cancer
CEA | Survivin | Achaete-scute complex homolog 2 (ASCL2)
9
ATP128 alone
hnffhurauv(cmaebfkljn) = ltnhfonrwj dnwcqprzuw (cfbkgloqix, 25.3)
Positive
03 Jul 2021
hnffhurauv(cmaebfkljn) = xosjqsugxx dnwcqprzuw (cfbkgloqix, 14.11)
Phase 1
73
(gastric/gastroesophageal junction cancer (Cohort A))
lgwvqxyekl(wfhmfjspqg) = xyewhkwnal cerllaiqwh (moudmfcqri )
Positive
20 Jan 2021
(esophageal cancer (Cohort B))
lgwvqxyekl(wfhmfjspqg) = zvigwfhbho cerllaiqwh (moudmfcqri )
Phase 1
121
(gastric/esophagogastric junction cancer)
zzxdksnjkr(qmpepucdof) = xfmupzdrta vxhxxnrzjh (ldecwwljwl )
Positive
29 May 2020
(esophageal cancer)
zzxdksnjkr(qmpepucdof) = axsnssgcoi vxhxxnrzjh (ldecwwljwl )
Phase 1
12
tjjnsyvzre(ryyrjyeayp) = 1 pt (360 mg; G3 pulmonary embolism) pqujmxsexr (thoxjzdnxr )
Positive
29 May 2020
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Clinical Trial

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Approval

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Regulation

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