Last update 21 Nov 2024

INV-1120

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
EP4
Mechanism
EP4 antagonists(Prostanoid EP4 receptor antagonists), Immunomodulators
Therapeutic Areas
Neoplasms
Active Indication
Metastatic Solid TumorAdvanced Malignant Solid NeoplasmNeoplasm Metastasis
Inactive Indication-
Originator Organization
Ionova Life Science Co., Ltd.Ionova Life Science Co., Ltd.Startup
Active Organization
Foshan Ionova Biotherapeutics Co., Ltd.Shenzhen Ionova Life Sciences Co., Ltd.
Inactive Organization
Merck Sharp & Dohme LLCIonova Life Science Co., Ltd.Ionova Life Science Co., Ltd.Startup
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with INV-1120
CTR20211872 / RecruitingPhase 1
INV-1120在局部晚期/转移性实体瘤患者中的首次人体、开放式、I期（剂量递增）临床试验
[Translation] A first-in-human, open-label, Phase I (dose-escalation) clinical trial of INV-1120 in patients with locally advanced/metastatic solid tumors
NCT04443088 / RecruitingPhase 1
A Phase 1a/1b, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Evidence of Antitumor Activity of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
100 Clinical Results associated with INV-1120
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100 Translational Medicine associated with INV-1120
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100 Patents (Medical) associated with INV-1120
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100 Deals associated with INV-1120
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 3
US
Merck Sharp & Dohme LLC
26 Jun 2020
Solid tumorPhase 3
US
Ionova Life Science Co., Ltd.Ionova Life Science Co., Ltd.Startup
26 Jun 2020
Metastatic Solid TumorPhase 1
CN
Foshan Ionova Biotherapeutics Co., Ltd.
10 Sep 2021
Advanced Malignant Solid NeoplasmPhase 1
US
Shenzhen Ionova Life Sciences Co., Ltd.
26 Jun 2020
Neoplasm MetastasisPhase 1
US
Shenzhen Ionova Life Sciences Co., Ltd.
26 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
CTR20211872 (ASCO2023)
ManualManual
Phase 1
HR-positive/HER2-low Solid Tumors
9
(vmsiauemna) = pgnligajui iegqyebfhb (bljareazis )
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Positive
31 May 2023
(60mg)
(vmsiauemna) = sickoemwwf iegqyebfhb (bljareazis )
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NCT04443088 (SITC2022)
ManualManual
Phase 1
HR-positive/HER2-low Solid Tumors
24
(qdntkidiie) = eyxiysodip debwcqujua (npgkdfouwn )
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Positive
01 Nov 2022
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Approval

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Regulation

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