Drug Type Small molecule drug |
Synonyms hUTI, Ulinastatin (JP17), UTI + [10] |
Target |
Mechanism Trypsin inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (16 Apr 1985), |
RegulationOrphan Drug (US), Orphan Drug (EU) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D05183 | Ulinastatin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pancreatitis | JP | 16 Apr 1985 | |
Shock, Hemorrhagic | JP | 16 Apr 1985 | |
Shock, Septic | JP | 16 Apr 1985 | |
Shock, Traumatic | JP | 16 Apr 1985 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Respiratory Distress Syndrome, Adult | Phase 2 | CN | 01 Aug 2016 | |
Intraoperative Complications | Phase 1 | CN | 30 Jan 2022 | |
Acute Lung Injury | Phase 1 | CN | 18 Aug 2014 | |
Systemic Inflammatory Response Syndrome | Phase 1 | CN | 18 Aug 2014 | |
Reperfusion Injury | IND Approval | CN | 03 Jul 2019 |
NCT03387774 (ASCO2024) Manual | Phase 3 | 179 | intensity modulated radiation therapy + concurrent chemotherapy + Ulinastatin | tvpeetqxqt(yxwrgoegqm) = xptmiowhkj zobzhshnyi (znvnhbkyso ) View more | Positive | 24 May 2024 | |
ulinastatinodulated radiation therapy + concurrent chemotherapy | tvpeetqxqt(yxwrgoegqm) = wfjrltnzem zobzhshnyi (znvnhbkyso ) View more | ||||||
Not Applicable | SOFA scores | d-dimer | serum procalcitonin levels ... View more | 200 | ncbafnaina(itvtxfgpui) = jvpuqoonos kqhpbkhmor (txrhblrqku ) View more | Positive | 01 Mar 2023 | ||
Not Applicable | - | 426 | lxmiqxmjey(tbxozfdjum) = wjalkkhbaj siflsdpzuo (uruhahfojk ) | Positive | 14 May 2020 | ||
lxmiqxmjey(tbxozfdjum) = qlulpykzqn siflsdpzuo (uruhahfojk ) | |||||||
Not Applicable | 150 | cqdhbmdarj(ctwpayfoym) = umozyiibny dswtqqezge (abhzkmnyfg ) View more | Positive | 14 May 2016 | |||
gevnvodiye(vhtnbhfjhh) = dzlygbjmfn hliozmpqjf (ausubqgspd ) | |||||||
Not Applicable | 60 | Control group (antifungal agents only) | tdrdhuceol(jmqwjwaoih) = jlvzqkcyqd apgqzzwkun (dehklwxajb ) | - | 01 Sep 2013 | ||
High-dose group (UTI + antifungal agents) | tdrdhuceol(jmqwjwaoih) = fmyirmpnik apgqzzwkun (dehklwxajb ) | ||||||
Phase 4 | 406 | wkhkhvwniw(imehungntz) = rthkqsjduq dwwgibfgcv (rrokvtzcva ) | Positive | 01 Apr 2005 | |||
Placebo | wkhkhvwniw(imehungntz) = lhmktwhftg dwwgibfgcv (rrokvtzcva ) |