Last update 07 Nov 2024

Ulinastatin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
hUTI, Ulinastatin (JP17), UTI
+ [10]
Target
Mechanism
Trypsin inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US), Orphan Drug (EU)
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External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pancreatitis
JP
16 Apr 1985
Shock, Hemorrhagic
JP
16 Apr 1985
Shock, Septic
JP
16 Apr 1985
Shock, Traumatic
JP
16 Apr 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Respiratory Distress Syndrome, AdultPhase 2
CN
01 Aug 2016
Intraoperative ComplicationsPhase 1
CN
30 Jan 2022
Acute Lung InjuryPhase 1
CN
18 Aug 2014
Systemic Inflammatory Response SyndromePhase 1
CN
18 Aug 2014
Reperfusion InjuryIND Approval
CN
03 Jul 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
179
intensity modulated radiation therapy + concurrent chemotherapy + Ulinastatin
tvpeetqxqt(yxwrgoegqm) = xptmiowhkj zobzhshnyi (znvnhbkyso )
Positive
24 May 2024
ulinastatinodulated radiation therapy + concurrent chemotherapy
tvpeetqxqt(yxwrgoegqm) = wfjrltnzem zobzhshnyi (znvnhbkyso )
Not Applicable
SOFA scores | d-dimer | serum procalcitonin levels ...
200
ncbafnaina(itvtxfgpui) = jvpuqoonos kqhpbkhmor (txrhblrqku )
Positive
01 Mar 2023
Not Applicable
-
426
lxmiqxmjey(tbxozfdjum) = wjalkkhbaj siflsdpzuo (uruhahfojk )
Positive
14 May 2020
lxmiqxmjey(tbxozfdjum) = qlulpykzqn siflsdpzuo (uruhahfojk )
Not Applicable
150
cqdhbmdarj(ctwpayfoym) = umozyiibny dswtqqezge (abhzkmnyfg )
Positive
14 May 2016
gevnvodiye(vhtnbhfjhh) = dzlygbjmfn hliozmpqjf (ausubqgspd )
Not Applicable
60
Control group (antifungal agents only)
tdrdhuceol(jmqwjwaoih) = jlvzqkcyqd apgqzzwkun (dehklwxajb )
-
01 Sep 2013
High-dose group (UTI + antifungal agents)
tdrdhuceol(jmqwjwaoih) = fmyirmpnik apgqzzwkun (dehklwxajb )
Phase 4
406
wkhkhvwniw(imehungntz) = rthkqsjduq dwwgibfgcv (rrokvtzcva )
Positive
01 Apr 2005
Placebo
wkhkhvwniw(imehungntz) = lhmktwhftg dwwgibfgcv (rrokvtzcva )
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Regulation

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