Last update 19 Jul 2024

Cevimeline Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Cevimeline, Cevimeline hydrochloride (USAN)
+ [17]
Mechanism
M3 receptor agonists(Muscarinic acetylcholine receptor M3 agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC20H38Cl2N2O3S2
InChIKeyZSTLCHCDLIUXJE-OFJNZLMZSA-N
CAS Registry153504-70-2

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Sjogren's Syndrome
JP
20 Jun 2001
Sjogren's Syndrome
JP
20 Jun 2001
Sjogren's Syndrome
JP
20 Jun 2001
Antisynthetase Syndrome
US
11 Jan 2000
Xerostomia
US
11 Jan 2000
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
ComplicationPhase 3
US
01 Jun 2001
Head and Neck NeoplasmsPhase 3
US
01 Jun 2001
ToxicityPhase 3
US
01 Jun 2001
Alzheimer DiseasePhase 3
JP
-
DementiaPhase 2
JP
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
15
(Cevimeline)
ecxbwytljw(rpijfggvjj) = vttxggjvkn ahjkaefmsp (fqquhwurju, scjcyxwmcy - vbfttcnmsc)
-
06 Aug 2014
(Pilocarpine)
ecxbwytljw(rpijfggvjj) = kvrivvwrxs ahjkaefmsp (fqquhwurju, kimtvwhdup - mpaltfskea)
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Approval

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Regulation

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