Last update 26 Feb 2026

MK-8655

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MK 8655
Target-
Action-
Mechanism-
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Diabetes Mellitus, Type 2
Originator Organization
Merck & Co., Inc.Merck & Co., Inc.
Active Organization-
Inactive Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.Merck GmbH
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with MK-8655
NCT01640873
/ CompletedPhase 1
A Randomized Double-Blind Placebo-Controlled Single and Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-8655 in Subjects With Type 2 Diabetes
100 Clinical Results associated with MK-8655
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100 Translational Medicine associated with MK-8655
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100 Patents (Medical) associated with MK-8655
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100 Deals associated with MK-8655
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1-
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
19 Sep 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT01640873 (8655-002 | MK-8655-002, CTgov)
Phase 1
Diabetes Mellitus, Type 2
33
(MK-8655 80 mg/MK-8655 320 mg)
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-
13 Nov 2018
Placebo
(Placebo)
yvqhrntsbx = zwswyjenht qgsvtykhyz (wdijdjzxhl, aagojgkycg - klgpnyepzy)
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Deal

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Clinical Trial

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Approval

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Regulation

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