Last update 20 Mar 2025

CLDN6 RNA-LPX

Overview

Basic Info

Drug Type
Therapeutic vaccine, mRNA vaccine
Synonyms-
Target
CLDN6
Action
modulators, stimulants
Mechanism
CLDN6 modulators(Claudin 6 modulators), Immunostimulants
Therapeutic Areas
Neoplasms
Active Indication
Solid tumor
Inactive Indication-
Originator Organization
BioNTech Cell & Gene Therapies GmbH
Active Organization
BioNTech Cell & Gene Therapies GmbH
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CLDN6 RNA-LPX
NCT04503278
/ RecruitingPhase 1
Phase I/IIa, First-in-human (FIH), Open-label, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of CLDN6 CAR-T With or Without CLDN6 RNA-LPX in Patients With CLDN6-positive Relapsed or Refractory Advanced Solid Tumors
100 Clinical Results associated with CLDN6 RNA-LPX
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100 Translational Medicine associated with CLDN6 RNA-LPX
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100 Patents (Medical) associated with CLDN6 RNA-LPX
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100 Deals associated with CLDN6 RNA-LPX
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 1
Australia
BioNTech Cell & Gene Therapies GmbH
16 Sep 2020
Solid tumorPhase 1
Sweden
BioNTech Cell & Gene Therapies GmbH
16 Sep 2020
Solid tumorPhase 1
Germany
BioNTech Cell & Gene Therapies GmbH
16 Sep 2020
Solid tumorPhase 1
Netherlands
BioNTech Cell & Gene Therapies GmbH
16 Sep 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT04503278 (BNT211-01, ESMO2024)
ManualManual
Phase 1
CLDN6-positive Solid Tumors
CLDN6+
59
(lcufjwidzb) = including related to LD, occurred in 52 pts (88%). winciaquil (liejzaedfv )
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Positive
15 Sep 2024
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Approval

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Regulation

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