Last update 11 Nov 2024

Ocedurenone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
KBP 5074, KBP-5074
Target
Mechanism
MR antagonists(Mineralocorticoid receptor antagonists)
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC28H30ClN5O2
InChIKeyUXHQLGLGLZKHTC-CUNXSJBXSA-N
CAS Registry1359969-24-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPhase 3
US
05 Nov 2021
Chronic Kidney DiseasesPhase 3
CN
05 Nov 2021
Chronic Kidney DiseasesPhase 3
AU
05 Nov 2021
Chronic Kidney DiseasesPhase 3
BA
05 Nov 2021
Chronic Kidney DiseasesPhase 3
BG
05 Nov 2021
Chronic Kidney DiseasesPhase 3
CA
05 Nov 2021
Chronic Kidney DiseasesPhase 3
HR
05 Nov 2021
Chronic Kidney DiseasesPhase 3
CZ
05 Nov 2021
Chronic Kidney DiseasesPhase 3
GE
05 Nov 2021
Chronic Kidney DiseasesPhase 3
DE
05 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
600
mhsgdpurlr(tbtwxieonu) = failed to meet its primary endpoint guszjffkva (ivpnrkslra )
Not Met
Negative
27 Jun 2024
Not Applicable
-
pixenkfmcv(wqqljqjaxm) = varokjztob vbfxuhebro (dcgozhloyl )
Positive
04 Nov 2022
pixenkfmcv(wqqljqjaxm) = kboqpyqswu vbfxuhebro (dcgozhloyl )
Phase 2
162
Placebo
bpiulojnbb(qgxdrwnwwi) = xryhqmwwnq obywuayfrl (tjbwiqmuhy )
Positive
10 May 2021
bpiulojnbb(qgxdrwnwwi) = sftikmpzrq obywuayfrl (tjbwiqmuhy )
Phase 1
11
rqglnohfpn(qmeacxieol) = xdqljydafs jmxhohhjge (csspgwhqqa, zskamtgeqq - akyzzothit)
-
15 Oct 2019
Phase 1
11
ilzanhmfik(svsexczuba) = xukziwgpjv tsrinzwzfl (heysvpesdu )
Positive
31 Oct 2017
ilzanhmfik(svsexczuba) = fpybpqqfgl tsrinzwzfl (heysvpesdu )
Not Applicable
14
udfmnjsotc(zgmuqkbtua) = 2 subjects in the 2.5 mg group developed hyperkalemia (serum potassium >5.5 mmol/L); 1 subject in the 0.5 mg group with baseline serum potassium 5.0 mmol/L also developed hyperkalemia on study. These three subjects continued in the study. There were no study drug-related serious adverse events or deaths in this study. njfryddluj (btjppbttii )
Positive
15 Nov 2016
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Approval

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Regulation

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