Lipoic acid

WEDNESDAY, Dec. 17, 2025 — An over-the-counter supplement called lipoic acid might help slow the loss of gray matter in the brains of people with progressive multiple sclerosis ( MS ), a new clinical trial has found. Lipoic acid (also called alpha-lipoic acid) did not improve patients’ walking speed, which was the main outcome being measured by researchers. But MRI scans revealed the supplement did appear to slow brain atrophy, researchers reported Dec. 15 in the journal Neurology . “It didn’t work clinically in progressive multiple sclerosis the way we hoped,” said lead researcher Dr. Rebecca Spain , an associate professor of neurology at Oregon Health & Science University in Portland. “However, the slowing of brain atrophy that we saw in MRI images suggests that we may yet be on the right track, especially if we can find a better way to deliver the beneficial effects of an antioxidant like lipoic acid,” she said in a news release. Lipoic acid is a naturally occurring fatty acid found in many foods like yeast, spinach, broccoli, potatoes and organ meats like liver or kidney, according to Drugs.com . The supplement is taken for diabetic neuropathy , and its action in the body makes it a potentially promising treatment for MS, researchers said in background notes. Specifically, lipoic acid’s anti-inflammatory and antioxidant effects might protect against the damage that MS does to myelin, the protective sheath that covers nerve fibers, as well as to the underlying nerves, researchers said. For the new study, researchers recruited 54 people with progressive MS, a form of the disease in which brain function becomes steadily worse with no periods of remission. These patients took a daily 1,200-milligram dose of lipoic acid over two years, and their progress was compared to that of 61 other MS patients taking a placebo. This relatively high dose of lipoic acid was used to try and make sure enough of the supplement got into patients’ brains, researchers said. “Lipoic acid is lipophobic,” Spain said. “It does not cross the blood-brain barrier and get into the central nervous system very easily.” The results of this trial will be added to other studies of lipoic acid to further assess the supplement’s potential benefits, she said. “We are going to learn more about whether lipoic acid is worth taking if you have progressive MS,” Spain said. “I am cautiously optimistic.” Sources Oregon Health & Science University, news release, Dec. 15, 2025

LOUISVILLE, KY, UNITED STATES, August 4, 2025 / EINPresswire.com / -- Patients with traumatic brain injuries (TBI) and stroke symptoms are finding new hope in Louisville, Kentucky, where Dr. Rafael F. Cruz MD and his team at Kentuckiana Integrative Medicine offer Perispinal Etanercept therapy—an innovative procedure that’s drawing patients from across the United States, Canada and Europe seeking relief from debilitating symptoms often unaddressed by conventional medicine. Traumatic brain injuries and strokes can leave patients with life-altering challenges, including memory loss, chronic pain, speech difficulties, and mobility issues. While conventional therapy focuses on managing symptoms, Dr. Cruz’s approach in using Perispinal Etanercept, has shown rapid and dramatic results. “Perispinal Etanercept is a game-changer for patients who have been told there’s no hope for improvement,” says Dr. Cruz, a nationally recognized leader in integrative medicine. “We’ve seen patients regain speech, mobility, and cognitive function within hours of therapy. It’s truly life-changing.” What Is Perispinal Etanercept Therapy? Perispinal Etanercept is an anti-TNF (tumor necrosis factor) biologic that targets chronic inflammation in the brain—a key driver of ongoing neurological dysfunction after TBI or stroke. Administered via a specialized injection technique, the therapy allows the medication to reach the brain and cerebrospinal fluid quickly, often resulting in noticeable improvements in speech, mobility, and pain within hours. Dr. Cruz and his team at Kentuckiana Integrative Medicine are among the few clinics in the U.S. offering this advanced therapy, making Louisville a destination for patients worldwide. Real Stories of Recovery from Kentuckiana Integrative Medicine: Patients from all over the country have shared inspiring stories of recovery after being seen at Kentuckiana Integrative Medicine. > Eduard Wilks., a stroke survivor, went from using a walker to taking independent steps after therapy. > Louis Meier, Parkinson's shuffling gate and history of falls corrected in hours > Mike Bonin., an IT engineer, has made significant strides in overcoming paralysis and balance issues following his therapy. The Potential for Stroke Recovery: While not a patient at the clinic, Linda's story is a powerful example of the remarkable recovery that is possible. Linda, a teacher from Connecticut, regained her speech and improved her ability to walk three years after a massive stroke. Watch these patient video testimonials and many more on our website . Kentuckiana Integrative Medicine Specializes in Advanced Therapies for Complex Conditions: 1. Neurological and Brain Injury Therapies: TBI, stroke, Parkinson’s, ALS, and Long Haulers Syndrome with innovative solutions like Perispinal Etanercept and regenerative therapies. 2. Regenerative Medicine Injections: Offering regenerative messenger signaling “stem “ cellular injection therapy, hyper-concentrated PRP (enhanced with procaine, photobiomodulation, and B vitamins), Prolozone Therapy and Prolozone Therapy for pain and tissue repair. 3. Ketamine Therapy: For mental health challenges like PTSD, depression, and chronic pain. 4. Wellness Therapies: Using advanced PRP and regenerative messenger signaling “stem “ cellular injection therapy for enhanced results. 5. Heart Disease Reversal Therapies: IV EDTA Chelation and IV Phospholipids for cardiovascular health. 6. Cancer Support Therapies: IV Ozone, IV DMSO, IV Alpha Lipoic Acid, IV Vitamin C Therapy, Low Dose Naltrexone and other Repurposed Medications to boost immunity and support overall well-being. Take the Next Step! If you or a loved one is living with the effects of TBI or stroke, Kentuckiana Integrative Medicine invites you to explore the possibilities of Perispinal Etanercept therapy. > Request FREE information at www.ReGenMedKy.com — takes just 30 seconds. > Schedule a consultation by calling 812-913-4416. Consultations are $400, but the fee is credited back if you invest $2,500 or more in your plan. Don’t let brain trauma define your future. Join the growing number of patients from across the U.S. who are finding hope and healing in Louisville with Dr. Cruz’s innovative therapies. About Kentuckiana Integrative Medicine Kentuckiana Integrative Medicine, led by Dr. Rafael F. Cruz MD, is a leading clinic specializing in regenerative and integrative medicine. Located in Louisville, KY, the clinic serves patients from the Kentuckiana region and beyond, offering cutting-edge therapies for TBI, stroke, Parkinson’s, and other neurological conditions. Read our disclaimer here: regenmedky.com/fda-disclaimer Kentuckiana Integrative Medicine Kentuckiana Integrative Medicine +1 812-913-4416 email us here Stroke, Parkinsons, & Traumatic Brain Injury Therapies Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.