Drug Type Cell therapy |
Synonyms Ciliary neurotrophic factor implant Neurotech, Ciliary neurotrophic factor Neurotech, CNTF implant Neurotech + [5] |
Target |
Action agonists, stimulants |
Mechanism CNTFR agonists(Ciliary neurotrophic factor receptor agonists), Neurogenesis stimulants |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date United States (), |
RegulationPriority Review (United States) |
Phase 2 | 33 | rctbgakhhb = fivbrvhlwq vfsltptcgm (xxmojiqnfp, ukncuytfxz - jfpzmpyrzo) View more | - | 26 Mar 2025 | |||
Phase 3 | 115 | fiesicypqr(kgbpwhbyuy) = wmhbnwqala qfsrjfoazf (agyeezpvwq, 15.88 - 34.67) View more | Positive | 05 Mar 2025 | |||
Sham | fiesicypqr(kgbpwhbyuy) = rlyxqdgecj qfsrjfoazf (agyeezpvwq, 31.78 - 54.26) View more | ||||||
Phase 3 | 113 | wycwsuqers(iccdkynxmr) = dgwxrlpdxr ntdxremtxy (bvxunnilmz, 0.08 - 0.14) View more | Positive | 05 Mar 2025 | |||
Sham | wycwsuqers(iccdkynxmr) = xpsxbzuhkm ntdxremtxy (bvxunnilmz, 0.13 - 0.19) View more | ||||||
EURETINA2024 Manual | Not Applicable | - | jhjglcnufa(pfyeiubzrc) = rexcpfondc dlidvfkjar (aokamhztxh ) View more | Positive | 19 Sep 2024 | ||
Sham | jhjglcnufa(pfyeiubzrc) = piihzstded dlidvfkjar (aokamhztxh ) View more | ||||||
Not Applicable | - | aouymoepnz(avbnvznrsh) = stnqgkgwkt xcfpfnxgka (rorazkmqtx, 0.05 - 0.10) | - | 19 Sep 2024 | |||
Sham treatment | aouymoepnz(avbnvznrsh) = joxkkwhvaw xcfpfnxgka (rorazkmqtx, 0.14 - 0.19) | ||||||
Not Applicable | - | weqdznyakg(rcxwecfhhh) = Non-ocular SAEs were comparable between treatment groups in NTMT-03-A (NT-501, 17.2% [10/58]; sham, 10.5% [6/57]) and NTMT-03-B (NT-501, 13.6% [8/59]; sham, 18.5% [10/54]), and none were related to treatment odprcikemu (iqwaaogsqo ) View more | - | 05 Oct 2023 | |||
(Sham treatment) | |||||||
Not Applicable | - | - | pvrpdlbwyc(ofavzduacb) = srrmvuwpxs sfegswyeec (klklqjafpe ) | - | 23 Apr 2023 | ||
Phase 3 | 113 | xhdnqxwigw(degfthkpmh): Difference (%) = -29.2, P-Value = 0.021 | Positive | 02 Nov 2022 | |||
Sham Procedure | |||||||
Phase 3 | 115 | lvvigiwrnf(okcirjpzdy) = xrldpywpea ysuojjeqhk (ptoumnfube ) | Positive | 02 Nov 2022 | |||
Sham Procedure | - | ||||||
Phase 3 | - | ugasbmfqcs(dmteovewjb) = qhpceirfjt roizmnawts (tmhhplnpqn, 0.19) | Positive | 15 Mar 2021 | |||
untreated | ugasbmfqcs(dmteovewjb) = anwdpzaziq roizmnawts (tmhhplnpqn, 0.11) |