Synonyms ciliary neurotrophic factor receptor, Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha + [3] |
Introduction Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1 (PubMed:26858303). Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1 (PubMed:19386761). |
Target |
Mechanism CNTFR agonists [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseNDA/BLA |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism CNTFR agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhasePhase 3 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism- |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseDiscovery |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date01 Apr 2025 |
Sponsor / Collaborator |
Start Date13 Aug 2021 |
Sponsor / Collaborator |
Start Date15 May 2021 |
Sponsor / Collaborator |