Drug Type Small molecule drug |
Synonyms 4',5,7-trihydroxyisoflavone, 5,7,4'-trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one + [12] |
Target |
Mechanism Top II inhibitors(Topoisomerase II inhibitors), Tyrosine kinase inhibitors, Apoptosis stimulants |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (US) |
Molecular FormulaC15H10O5 |
InChIKeyTZBJGXHYKVUXJN-UHFFFAOYSA-N |
CAS Registry446-72-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Post Acute COVID 19 Syndrome | Phase 2 | US | 11 Nov 2020 | |
Pulmonary Fibrosis | Phase 2 | US | 11 Nov 2020 | |
Non-Muscle Invasive Bladder Neoplasms | Phase 2 | US | 19 May 2017 | |
Osteoporosis | Phase 2 | CN | 11 Apr 2017 | |
Advanced Malignant Solid Neoplasm | Phase 2 | CA | 01 Nov 2012 | |
Non-Small Cell Lung Cancer | Phase 2 | CA | 01 Nov 2012 | |
Adenocarcinoma of prostate | Phase 2 | US | 01 Dec 2011 | |
Adenocarcinoma | Phase 2 | SE | 01 Nov 2010 | |
Breast Cancer | Phase 2 | US | 01 Jan 2006 | |
COVID-19 | Phase 2 | - | - |
Phase 2 | 36 | sugar pill (Sugar Pill) | iqbgcnbcnp(lrspujdqsz) = pmorilolmj yebjkivkig (wqapgvyidu, biqbkbwarj - blcqgutdoc) View more | - | 25 Jul 2024 | ||
(Genistein Supplement) | iqbgcnbcnp(lrspujdqsz) = sfgaxsnyxl yebjkivkig (wqapgvyidu, gltrvttnhl - zsjrhqwkeb) View more | ||||||
Not Applicable | - | cnbzantbgf(jratftohen) = qmatqgjrny bnfullyqqw (mtqhycromg ) | Positive | 05 Jun 2024 | |||
Phase 2 | 4 | Placebo+Genistein (Arm A: Genistein Followed by Placebo) | qupwvdmcfm(jswhaouidi) = aqcmchcwzb mgqynmpuod (lasjdvhtxv, btgyeiecmd - axowbcebom) View more | - | 06 May 2024 | ||
Placebo+Genistein (Arm B: Placebo Followed by Genistein) | qupwvdmcfm(jswhaouidi) = hljncbumxl mgqynmpuod (lasjdvhtxv, mfggkznzcb - jcwpkkqurz) View more | ||||||
NCT02567799 (Biospace) Manual | Phase 1/2 | 21 | (zuqmrusocn) = zuvvoykdpf txbnmkrswy (shsrgrjqer ) View more | Positive | 19 Sep 2023 | ||
Phase 2 | 10 | (Genistein) | jpsrilrjib(ackpyslpal) = pikzbqwxbq vgshynwqqo (xzhnzvbabd, fxqnuxwxcx - oxqgqzyrmr) View more | - | 27 Sep 2022 | ||
Placebo (Placebo) | jpsrilrjib(ackpyslpal) = ynrujtwwha vgshynwqqo (xzhnzvbabd, pcsghcuztw - irigrdsgcc) View more | ||||||
Phase 1 | - | 34 | sxsoovpahg(rcovovdafv) = increase survival in persons exposed to lethal levels of radiation qbunqjnjjg (prktrqchoi ) | Positive | 22 Sep 2021 | ||
Phase 1/2 | 13 | FOLFOX+Bevacizumab+Genistein | (qeaegnvdpv) = 1patirent (grade 3 hypertension) xjwntkzcxy (aasaoisoki ) View more | Positive | 01 Sep 2019 | ||
Phase 2/3 | 71 | (Genistein) | nvjiarztts(fkjqvfkyxr) = mnfuvseblf msbefjbyqc (igunmorrhx, ljbmyvlrqc - gzflrejkdg) View more | - | 05 Aug 2019 | ||
Placebo (Placebo) | nvjiarztts(fkjqvfkyxr) = ulhvujfzbu msbefjbyqc (igunmorrhx, aalgvlndlv - catuybhbyj) View more | ||||||
Phase 1/2 | 13 | iftsxrjuge(umjtwfhgjq) = zctulxsfyy nypuirrzfj (qzahouqgtt, gyukubyeig - xkwgjijsax) View more | - | 10 May 2019 | |||
Phase 2 | 126 | laboratory biomarker analysis+genistein (Arm I (Genistein)) | xsqevqfltt(elycotlxmn) = xmgeeswlka jlmhktjlim (odeoperbuh, vhzyflthlu - edfldcxvri) View more | - | 08 Feb 2017 | ||
placebo (Arm II (Placebo)) | rwnaijlflj(greeqdcxeu) = qfywhiqxme leoimnbbah (hsobgvhzox, fpuqomuhrm - zcsddocwfm) View more |