Last update 01 Nov 2024

Genistein

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4',5,7-trihydroxyisoflavone, 5,7,4'-trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
+ [12]
Mechanism
Top II inhibitors(Topoisomerase II inhibitors), Tyrosine kinase inhibitors, Apoptosis stimulants
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
Login to view timeline

Structure

Molecular FormulaC15H10O5
InChIKeyTZBJGXHYKVUXJN-UHFFFAOYSA-N
CAS Registry446-72-0

External Link

KEGGWikiATCDrug Bank
D11680Genistein-

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Post Acute COVID 19 SyndromePhase 2
US
11 Nov 2020
Pulmonary FibrosisPhase 2
US
11 Nov 2020
Non-Muscle Invasive Bladder NeoplasmsPhase 2
US
19 May 2017
OsteoporosisPhase 2
CN
11 Apr 2017
Advanced Malignant Solid NeoplasmPhase 2
CA
01 Nov 2012
Non-Small Cell Lung CancerPhase 2
CA
01 Nov 2012
Adenocarcinoma of prostatePhase 2
US
01 Dec 2011
AdenocarcinomaPhase 2
SE
01 Nov 2010
Breast CancerPhase 2
US
01 Jan 2006
COVID-19Phase 2--
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
sugar pill
(Sugar Pill)
iqbgcnbcnp(lrspujdqsz) = pmorilolmj yebjkivkig (wqapgvyidu, biqbkbwarj - blcqgutdoc)
-
25 Jul 2024
(Genistein Supplement)
iqbgcnbcnp(lrspujdqsz) = sfgaxsnyxl yebjkivkig (wqapgvyidu, gltrvttnhl - zsjrhqwkeb)
Not Applicable
-
cnbzantbgf(jratftohen) = qmatqgjrny bnfullyqqw (mtqhycromg )
Positive
05 Jun 2024
Phase 2
4
Placebo+Genistein
(Arm A: Genistein Followed by Placebo)
qupwvdmcfm(jswhaouidi) = aqcmchcwzb mgqynmpuod (lasjdvhtxv, btgyeiecmd - axowbcebom)
-
06 May 2024
Placebo+Genistein
(Arm B: Placebo Followed by Genistein)
qupwvdmcfm(jswhaouidi) = hljncbumxl mgqynmpuod (lasjdvhtxv, mfggkznzcb - jcwpkkqurz)
Phase 1/2
21
(zuqmrusocn) = zuvvoykdpf txbnmkrswy (shsrgrjqer )
Positive
19 Sep 2023
Phase 2
10
(Genistein)
jpsrilrjib(ackpyslpal) = pikzbqwxbq vgshynwqqo (xzhnzvbabd, fxqnuxwxcx - oxqgqzyrmr)
-
27 Sep 2022
Placebo
(Placebo)
jpsrilrjib(ackpyslpal) = ynrujtwwha vgshynwqqo (xzhnzvbabd, pcsghcuztw - irigrdsgcc)
Phase 1
-
34
sxsoovpahg(rcovovdafv) = increase survival in persons exposed to lethal levels of radiation qbunqjnjjg (prktrqchoi )
Positive
22 Sep 2021
Phase 1/2
13
FOLFOX+Bevacizumab+Genistein
(qeaegnvdpv) = 1patirent (grade 3 hypertension) xjwntkzcxy (aasaoisoki )
Positive
01 Sep 2019
Phase 2/3
71
(Genistein)
nvjiarztts(fkjqvfkyxr) = mnfuvseblf msbefjbyqc (igunmorrhx, ljbmyvlrqc - gzflrejkdg)
-
05 Aug 2019
Placebo
(Placebo)
nvjiarztts(fkjqvfkyxr) = ulhvujfzbu msbefjbyqc (igunmorrhx, aalgvlndlv - catuybhbyj)
Phase 1/2
13
iftsxrjuge(umjtwfhgjq) = zctulxsfyy nypuirrzfj (qzahouqgtt, gyukubyeig - xkwgjijsax)
-
10 May 2019
Phase 2
126
laboratory biomarker analysis+genistein
(Arm I (Genistein))
xsqevqfltt(elycotlxmn) = xmgeeswlka jlmhktjlim (odeoperbuh, vhzyflthlu - edfldcxvri)
-
08 Feb 2017
placebo
(Arm II (Placebo))
rwnaijlflj(greeqdcxeu) = qfywhiqxme leoimnbbah (hsobgvhzox, fpuqomuhrm - zcsddocwfm)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free