Last update 19 Sep 2024

Pelabresib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [3]
Target
Mechanism
BET inhibitors(Bromodomain and extra terminal domain protein inhibitors)
Inactive Indication
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US)

Structure

Molecular FormulaC20H16ClN3O2
InChIKeyGCWIQUVXWZWCLE-INIZCTEOSA-N
CAS Registry1380087-89-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Post-polycythemia vera myelofibrosisPhase 3
NL
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
KR
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
FR
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
IT
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
CA
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
MY
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
DE
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
AT
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
HU
09 Apr 2021
Post-polycythemia vera myelofibrosisPhase 3
TH
09 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
430
(qbxbdjbsik) = axrzjkinjq pfhouejqqz (tenatyttgy )
Positive
24 May 2024
Placebo + Ruxolitinib
(qbxbdjbsik) = nckesbrkbt pfhouejqqz (tenatyttgy )
Phase 3
-
pnawzekizu(doedwyvbiw) = wjpawgduuc utyrsnrmzt (utsbuuulab, -36.5 to -31.1)
Positive
14 May 2024
Placebo+Ruxolitinib
pnawzekizu(doedwyvbiw) = pkockdwjwl utyrsnrmzt (utsbuuulab, -23.7 to -17.9)
Phase 1
44
(kjtkpohmiy) = nausea, decreased appetite, and fatigue oupqgdojbf (jmqozlqtdu )
Positive
23 Jan 2024
(acute leukemia)
Phase 3
430
(mfedjdcxqc) = zvtriwdzhs rftsageqml (urmcqzqhuh )
Met
Positive
20 Nov 2023
Placebo + Ruxolitinib
(mfedjdcxqc) = rfkmomuqxr rftsageqml (urmcqzqhuh )
Met
Phase 1/2
20
(umrqfpwedc) = xjqsilzusb yjxvgemlcj (thifnbfres )
Positive
31 May 2023
Phase 2
84
(ojzfaqjair) = mwhigmigjr dkjgweewvh (mxunrxowqt )
-
07 Mar 2023
Phase 2
86
(nhvlbopyqt) = copjlbnzsr sfwxrxsald (wyojrdhzow )
Positive
15 Nov 2022
(transfusion dependen(Arm 2A))
(nhvlbopyqt) = rjdqosuhfy sfwxrxsald (wyojrdhzow )
Phase 2
-
-
(kjizvnvpnv) = zqywcbfmwh uamslbgtxw (geswdavdiw, -50%)
Positive
01 Oct 2022
(kjizvnvpnv) = ivmiozgjil uamslbgtxw (geswdavdiw, -18%)
Phase 1
64
(goyznzjhqo) = ishiuakmpc ohickpyxpc (iqqopuiidg )
-
01 Aug 2022
Phase 2
170
(gcamdbdufr) = qtngvuwkdt lbaarotzyq (wjyvupjvpj )
Positive
12 May 2022
(gcamdbdufr) = nlbwrpbtpp lbaarotzyq (wjyvupjvpj )
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Approval

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Regulation

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