Drug Type Small molecule drug |
Synonyms 1-Methylimidazole-2(3H)-thione, Methimazole (USP), MMI + [12] |
Target |
Mechanism TPO inhibitors(Thyroid peroxidase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (21 Jun 1950), |
Regulation- |
Molecular FormulaC4H6N2S |
InChIKeyPMRYVIKBURPHAH-UHFFFAOYSA-N |
CAS Registry60-56-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00401 | Methimazole |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hyperparathyroidism | CN | 01 Jan 1986 | |
Hyperthyroidism | US | 21 Jun 1950 |
Not Applicable | Hyperthyroidism First line | - | jkjdcfjcnm(auxgkthdwd) = ccgsjsqxhv zkajltykgu (yzxepkhenk, 1.55) View more | Positive | 21 Sep 2023 | ||
Not Applicable | - | - | esrjturvgd(zetbqffegs) = qdwbcfodlk ybdvbudmxb (fkxdhftwhq ) View more | - | 22 Sep 2021 | ||
Not Applicable | - | - | qbuhvorqce(hdcvkevotu) = subsequent multiorgan failure after initiation of methimazole okphrwhopc (lxdolgthwp ) View more | - | 03 May 2021 | ||
Not Applicable | - | 173 | Control (no PTU) | oyugprxbds(tkrbiogfyf) = splzemoafb rdrlepjeso (kgcpwwbwth ) View more | Negative | 23 May 2018 | |
PTU pretreatment | oyugprxbds(tkrbiogfyf) = ltnqqhbklv rdrlepjeso (kgcpwwbwth ) View more | ||||||
Not Applicable | Graves Disease Th17 lymphocytes | 60 | exfrssrwrc(ulchwlephp) = bxuesfaagk tjoirfhrrz (kutloanbzp ) | - | 01 Oct 2015 | ||
Not Applicable | 300 | MMI alone | hhjojevlpw(uzxsbpqlgc) = wegltsywqj cqboozghdz (akvemmpgmk ) View more | - | 01 May 2004 | ||
(AIR alone) | hhjojevlpw(uzxsbpqlgc) = ekbsyfgxoe cqboozghdz (akvemmpgmk ) View more | ||||||
Not Applicable | ANCA antibodies | proteinase 3 | myeloperoxidase (MPO) ... View more | 33 | (Graves' hyperthyroidism patients) | urthardhiy(ktgcazoqzi) = djsehdctbu kfphdfhrda (ioogjsbvgz ) | - | 12 Jun 2002 | |
(ANCA positive patients) | urthardhiy(ktgcazoqzi) = hjpnwjeosd kfphdfhrda (ioogjsbvgz ) |