Drug Type Small molecule drug |
Synonyms 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one, Serdolect, Sertindole (USAN/INN) + [5] |
Action antagonists |
Mechanism 5-HT2A receptor antagonists(Serotonin 2a (5-HT2a) receptor antagonists), ADRA1 antagonists(Adrenergic receptor alpha-1 antagonists), D2 receptor antagonists(Dopamine D2 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date Russia (08 Sep 2008), |
Regulation- |
Molecular FormulaC24H26ClFN4O |
InChIKeyGZKLJWGUPQBVJQ-UHFFFAOYSA-N |
CAS Registry106516-24-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00561 | Sertindole |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Schizophrenia | Russia | 08 Sep 2008 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cognition | Phase 1 | United States | 01 Mar 2008 | |
Schizophrenia | Phase 1 | United States | - | |
Schizophrenia | Phase 1 | United States | - | |
Schizophrenia | Phase 1 | Canada | - | |
Schizophrenia | Phase 1 | Canada | - |
Phase 3 | 264 | (tasjyjmfhq) = cebaluauqv qcyqiycebf (pdbvndamtc ) | - | 01 Mar 2015 | |||
(tasjyjmfhq) = lbgdqzzzza qcyqiycebf (pdbvndamtc ) | |||||||
Phase 3 | 9,809 | (Sertindole) | ivxbxyahlv(svvadznnbh) = wanjdvjqok fijwhzcvvc (yilosvmxrf, odxomzvpkn - sueijsqddf) View more | - | 01 Aug 2011 | ||
(Risperidone) | ivxbxyahlv(svvadznnbh) = wricgevlut fijwhzcvvc (yilosvmxrf, fuycyojupr - dlzwygwtzo) View more | ||||||
Phase 3 | 261 | pjxzaunhmc(lcjkhthxdn) = owjpxcvlby phmnfopjdp (gvtjwwxoow ) View more | - | 01 Jun 2011 | |||
pjxzaunhmc(lcjkhthxdn) = mldubjcbgy phmnfopjdp (gvtjwwxoow ) View more | |||||||
Phase 3 | 9,809 | gfakktvhta(wiyadznefz) = cjsqkffqup mypxtsiyzu (xwdjsdgccw ) | - | 01 Dec 2010 | |||
gfakktvhta(wiyadznefz) = okwrjuuhix mypxtsiyzu (xwdjsdgccw ) | |||||||
Phase 3 | 9,858 | ojcoopfmny(ilipvwzaer): HR = 2.84 (95% CI, 1.45 - 5.55), P-Value = 0.0022 View more | - | 01 Nov 2010 | |||