Last update 01 Nov 2024

Lixumistat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-Pyrrolidinecarboximidamide, N-[imino[[4-(trifluoromethoxy)phenyl]amino]methyl]-, acetate (1:1)
+ [5]
Mechanism
Mitochondrial complex I (NADH dehydrogenase) inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC13H16F3N5O
InChIKeyNGFUHJWVBKTNOE-UHFFFAOYSA-N
CAS Registry1422365-93-2

External Link

KEGGWikiATCDrug Bank
-Lixumistat--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 2-31 May 2023
Advanced Pancreatic AdenocarcinomaPhase 1
US
21 Oct 2022
Pancreatic CancerPhase 1
US
21 Oct 2022
Castration-Resistant Prostatic CancerPreclinical
US
31 May 2023
Gastrointestinal Stromal TumorsPreclinical
US
31 May 2023
Glioblastoma MultiformePreclinical
US
31 May 2023
Advanced Malignant Solid NeoplasmDiscovery
KR
09 Oct 2017
LymphomaDiscovery
KR
09 Oct 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
22
(wgjbmhhmnr) = vbztkmumat dlustiblqj (rmcumeufhh )
Positive
29 May 2020
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Clinical Trial

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Approval

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Regulation

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