Last update 21 Nov 2024

Lixumistat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-Pyrrolidinecarboximidamide, N-[imino[[4-(trifluoromethoxy)phenyl]amino]methyl]-, acetate (1:1)
+ [5]
Mechanism
Mitochondrial complex I (NADH dehydrogenase) inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC13H16F3N5O
InChIKeyNGFUHJWVBKTNOE-UHFFFAOYSA-N
CAS Registry1422365-93-2

External Link

KEGGWikiATCDrug Bank
-Lixumistat--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 2-31 May 2023
Advanced Malignant Solid NeoplasmPhase 2
KR
09 Oct 2017
LymphomaPhase 2
KR
09 Oct 2017
Advanced Pancreatic AdenocarcinomaPhase 1
US
21 Oct 2022
Pancreatic CancerPhase 1
US
21 Oct 2022
Castration-Resistant Prostatic CancerPreclinical
US
31 May 2023
Gastrointestinal Stromal TumorsPreclinical
US
31 May 2023
Glioblastoma MultiformePreclinical
US
31 May 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
22
(oghxrnmepw) = pjtxpkmfug wozopwzdmd (ymbgfypbho )
Positive
29 May 2020
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Clinical Trial

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Approval

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Regulation

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