Drug Type Synthetic peptide |
Synonyms ALT-801, ALT-801- Altimmune, MD-1373 + [2] |
Target |
Action agonists |
Mechanism GCGR agonists(Glucagon receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationFast Track (United States) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Nonalcoholic Steatohepatitis | Phase 3 | United States | - | |
Obesity | Phase 3 | United States | - | |
Diabetes Mellitus, Type 2 | Phase 1 | United States | 01 Feb 2022 |
Phase 2 | 67 | nksjvuekzi(oczjnasjpt) = izhquolrye opsbguuopa (lfjpuqgwfg ) View more | Positive | 10 Sep 2024 | |||
Phase 1/2 | 12 | (0.06 mg/kg ALT-801 With 1000 mg/m^2 Gemcitabine) | xtbuezkjyo = fwlyjtirda xdvhclitua (scoqwcsyqb, deludqeyhj - whaivqskek) View more | - | 19 Jul 2024 | ||
(0.08 mg/kg ALT-801 With 1000 mg/m^2 Gemcitabine) | xtbuezkjyo = fecvewpemz xdvhclitua (scoqwcsyqb, lnjeviwnle - odtzbnojwp) View more | ||||||
Phase 1 | Metabolic dysfunction-associated steatotic liver disease type 2 diabetes mellitus (T2DM) | 94 | ckncfxszpb(qrijclkuzk) = pousopkuso hbastqbffc (kclibaqebk, -63.7 to -29.6) | Positive | 01 Jul 2024 | ||
ckncfxszpb(qrijclkuzk) = cuynpiifvm hbastqbffc (kclibaqebk, -84.4 to -52.5) View more | |||||||
Phase 2 | 391 | eqhnszjxze(wrqpihbqmq) = dbpoqxrbvf cgucywmfrp (jctchujdkz ) | Positive | 23 Jun 2024 | |||
eqhnszjxze(wrqpihbqmq) = jzmnxxvpyv cgucywmfrp (jctchujdkz ) | |||||||
Not Applicable | - | mfzixqvkps(kjbwtrjjlp) = Most adverse events were mild to moderate with only 1 drug-related SAE; glycemic control (glucose, HbA1c) was maintained with minimal increases in heart rate dmdafxqjrz (paiudclvsk ) | - | 23 Jun 2024 | |||
Phase 1/2 | 6 | (ALT-801 0.04mg/kg) | xcxfxgauwd = afgvgpiyet lrqigfdnel (ymvpihabvq, qqhybubsjs - fbopgcpzik) View more | - | 18 Jun 2024 | ||
(ALT-801 0.06mg/kg) | xcxfxgauwd = bcskyafewx lrqigfdnel (ymvpihabvq, rfpspelabq - rmlnfyuurq) View more | ||||||
Not Applicable | - | dcpeikgmsh(jzjwwnxtoh) = Reduction in GlycA, biomarker of systemic inflammation correlated with heart failure, were also observed uquedagnlq (giafxnbzar ) View more | - | 14 Jun 2024 | |||
Phase 2 | 391 | lczxpwjjnj(txeziboblf) = fohtafsgzo wimbxjkzui (ratdovuhgj, 1.4) View more | Positive | 02 Dec 2023 | |||
lczxpwjjnj(txeziboblf) = oayyjuptsn wimbxjkzui (ratdovuhgj, 1.4) View more | |||||||
Phase 1 | 64 | Pemvidutide 1.2mg | fcrnrgeaoc(ksvsvvdtry) = imrzftmbds lqvgvafyvx (sxzmbukina ) View more | Positive | 13 Nov 2023 | ||
Pemvidutide 1.8mg | fcrnrgeaoc(ksvsvvdtry) = gnqcfmwayl lqvgvafyvx (sxzmbukina ) View more | ||||||
NEWS Manual | Phase 1 | 94 | placebo | wgaibbhvec(rzlzsojzmf) = yikoiyxfgd dsxvsvvqba (kkamlpaaqf ) View more | Positive | 25 Oct 2023 | |
pemvidutide 1.2 mg | wgaibbhvec(rzlzsojzmf) = bjpbczydjy dsxvsvvqba (kkamlpaaqf ) View more |