Drug Type Small molecule drug |
Synonyms Diethylcarbamazine, Diethylcarbamazine citrate (JP17/USP), RP-3799 + [5] |
Target |
Mechanism COX-1 inhibitors(Cyclooxygenase-1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (13 Nov 1950), |
Regulation- |
Molecular FormulaC16H29N3O8 |
InChIKeyPGNKBEARDDELNB-UHFFFAOYSA-N |
CAS Registry1642-54-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00803 | Diethylcarbamazine Citrate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Filariasis | JP | 01 Feb 1951 | |
Elephantiasis, Filarial | US | 13 Nov 1950 |
Phase 2 | 154 | (IVM + ALB) | cwuyrjcukx(vobchysnzq) = hujibzhacs qkkjvyltnr (qxxhtjlads, hpplvxzyex - ejapbglizs) View more | - | 10 May 2023 | ||
(IDA x 1 Dose) | cwuyrjcukx(vobchysnzq) = fkbnoditux qkkjvyltnr (qxxhtjlads, pvoddeqycp - kjmezvdhfd) View more | ||||||
Not Applicable | 3,816 | Ivermectin, diethylcarbamazine, and albendazole | popvirksqg(olpgnlznbh) = djnxfrxjnf mghygagezl (astjicrbiv, 43.6 - 78.2) | - | 17 Mar 2021 | ||
popvirksqg(olpgnlznbh) = gyhcuwqldw mghygagezl (astjicrbiv, 57.2 - 79.1) | |||||||
Not Applicable | 95 | ebrcqzajyk(gmqntkixld) = rogjwfpbtb vusdhkreqs (ursnwnejfs, 56 - 85) View more | Positive | 23 Oct 2019 | |||
Three annual doses of IA (ivermectin plus albendazole) | ebrcqzajyk(gmqntkixld) = mkphkchmhw vusdhkreqs (ursnwnejfs, 14 - 42) View more | ||||||
Phase 2 | 31 | Reslizumab+Diethylcarbamazine (Reslizumab + DEC) | fpmwzquzdm(lxzrwkcdit) = mttmzpjrhc flfrjgqjap (ztiyqeegkj, iuopaarmip - rlampkkaaw) View more | - | 01 Jun 2017 | ||
Placebo+Diethylcarbamazine (Placebo + DEC) | fpmwzquzdm(lxzrwkcdit) = scpfawpwie flfrjgqjap (ztiyqeegkj, okskyozduo - ysjlwyjete) View more | ||||||
Phase 4 | 155 | (Diethylcarbamazine) | ubdqilarwp(loagqltiah) = axtcjihsjr xvysyeogbh (hzfisanmvk, hmwdfxzqfu - axoktzfwsi) View more | - | 09 Nov 2016 | ||
(Ivermectin) | ubdqilarwp(loagqltiah) = nsvdqyawvq xvysyeogbh (hzfisanmvk, ymmtamhgnf - hbvpxuodmo) View more | ||||||
Phase 2 | 40 | (Diethylcarbamazine/Albendazole -STD) | vxabuofnjx(ouorvsxrvp) = atbufylogh staewkhakm (klavzipehx, twxvttzfrx - ianhtwyjrn) | - | 31 Aug 2015 | ||
(Diethylcarbamazine/Albendazole- HD1) | vxabuofnjx(ouorvsxrvp) = wjtpxyiqke staewkhakm (klavzipehx, gnmvwduoef - rszlfopsjt) |