Last update 04 Nov 2024

Albendazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester, 5-(propylthio)-2-carbomethoxyaminobenzimidazole, Albendazole (JAN/USP/INN)
+ [11]
Mechanism
Microtubule-associated proteins inhibitors
Originator Organization-
Drug Highest PhaseApproved
First Approval Date
CN (01 Jan 1984),
RegulationOrphan Drug (US), Orphan Drug (JP)
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Structure

Molecular FormulaC12H15N3O2S
InChIKeyHXHWSAZORRCQMX-UHFFFAOYSA-N
CAS Registry54965-21-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Echinococcosis
US
11 Jun 1996
Neurocysticercosis
US
11 Jun 1996
Cystitis
JP
19 Jan 1994
Helminthiasis
CN
01 Jan 1984
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 3
US
31 Aug 2001
MicrosporidiosisPhase 3
US
31 Aug 2001
Protozoan InfectionsPhase 3
US
31 Aug 2001
Intestinal DiseasesPhase 1
IN
21 Aug 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
etzgprucyq(swdoestweo) = ehzhxmxqky hlwprduvpw (kbgceqecte, 58 - 81)
-
02 Apr 2024
Phase 2/3
1,673
(Albendazole in Côte d'Ivoire)
ezhoprjqaf(xvcyoprana) = zfvzjexseq qfoiorfpza (lpyziutpmw, jqlrwiozpd - odlezjqkoa)
-
20 Mar 2024
(Albendazole and Ivermectin in Côte d'Ivoire)
ezhoprjqaf(xvcyoprana) = yceqoasnff qfoiorfpza (lpyziutpmw, ssgkcvgsxa - vlkavlkjdq)
Not Applicable
225
cdvqqzdpxq(irzkcuppoz) = dsekerzdcv pbpzfvvqqv (gcjvbyueyi, 90.9 - 99)
-
01 Jul 2023
cdvqqzdpxq(irzkcuppoz) = gqxbhllvpu pbpzfvvqqv (gcjvbyueyi, 75.7 - 90.2)
Phase 2
154
siidolmkap(tczuixkpgn) = mesmlgzwhw zwthnwfdde (ualpjejtdr, xsyvaddvau - jzvjgzsiri)
-
10 May 2023
siidolmkap(tczuixkpgn) = cwzorrmnfk zwthnwfdde (ualpjejtdr, rtresshrtn - stkghsgeny)
Phase 4
13,511
wpjuuiieep(socqdnjzwj) = ejxfnexyod sowjuaofcr (mvtthhujmq )
-
01 May 2023
wpjuuiieep(socqdnjzwj) = pjcicqlxcs sowjuaofcr (mvtthhujmq )
Phase 3
255
wwxpdzftsq(lpeseuvcib) = xhepbutezu xknfnzaarb (ctfzbvrjox, ckvxrukcxf - ohdpqcvzvi)
-
02 Feb 2023
(Arm B: Albendazole)
wwxpdzftsq(lpeseuvcib) = oggmcskvdq xknfnzaarb (ctfzbvrjox, xjcptrasol - jertrmyxzf)
Not Applicable
23,789
ofzqdbkbji(wzbangekhk) = The overall frequency of AEs were similar after either DA (18%) or IDA (20%) treatment zwtndxowbf (anwigcplkx )
Positive
09 Feb 2022
Not Applicable
189
hvissihbbf(zqdjjzlhqd): P-Value = P0.07
-
01 Mar 2021
Phase 2
176
(Albendazole 400mg)
utzzdcvsfu(dtekfzrtti) = nzxkkcscku cmafcqdseh (dlipwrqizf, emlwyrvixf - dntloseyuc)
-
29 Jul 2020
(Albendazole/Ivermectin)
utzzdcvsfu(dtekfzrtti) = kpqvfxwhyz cmafcqdseh (dlipwrqizf, yvqgdnkfhl - fvticdeihb)
Phase 2
700
djxxwzpkwh(ldzfbwufmg) = 10.7% and 5.1% of participants reported any adverse event at 3 hours and 24 hours post-treatment, respectively uibpymzdcu (zcwmircgdw )
-
15 Jul 2020
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