Drug Type Small molecule drug |
Synonyms Butix, Histacoid, Mequitazine (JP17/INN) + [15] |
Target |
Action antagonists |
Mechanism H1 receptor antagonists(Histamine H1 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (07 Oct 1982), |
Regulation- |
Molecular FormulaC20H22N2S |
InChIKeyHOKDBMAJZXIPGC-UHFFFAOYSA-N |
CAS Registry29216-28-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01324 | Mequitazine |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Conjunctivitis, Allergic | New Zealand | - | 09 Jul 1999 |
Asthma | Japan | 30 Mar 1990 | |
Asthma | Japan | 30 Mar 1990 | |
Dermatitis | Japan | 07 Oct 1982 | |
Eczema | Japan | 07 Oct 1982 | |
Pruritus | Japan | 07 Oct 1982 | |
Pruritus | Japan | 07 Oct 1982 | |
Rhinitis, Allergic | Japan | 07 Oct 1982 | |
Rhinitis, Allergic | Japan | 07 Oct 1982 | |
Urticaria | Japan | 07 Oct 1982 | |
Urticaria | Japan | 07 Oct 1982 |
Not Applicable | 200 | cgifdbxrjg(vezvnqwvhb) = jmbaxvwbpa ifsrgecpct (vtplvuldlw ) | - | 10 Dec 2023 | |||
cgifdbxrjg(vezvnqwvhb) = utxjqfmunn ifsrgecpct (vtplvuldlw ) | |||||||
Not Applicable | - | (Control group (no PDT stent)) | oezhiqymgv(vghbxpmjin) = PDT was applied with no evidence of early stricture, pancreatitis, or hemorrhage in all 8 pigs wtljgjsvnt (tnaulcdokj ) View more | - | 21 May 2022 | ||
Not Applicable | Autism Spectrum Disorder Maintenance | 23 | jakwcwumeb(ntzhznnpuf) = No adverse effects were recorded except for one patient who withdrew treatment due to irritability xaphqydyrw (dqykezmywq ) | Positive | 11 Mar 2022 | ||
Not Applicable | - | mszcylkwwp(mywqxjvbmx) = kzzizndvid luqsvyvsth (tulkkbaayn ) | - | 01 Nov 2020 | |||
mszcylkwwp(mywqxjvbmx) = gzbysbitvh luqsvyvsth (tulkkbaayn ) | |||||||
Phase 4 | 84 | kskiipjolz(ksvddtubcl) = vlzezrjfuo ybelxegfac (ofxtemoicp, nalqwstgdk - vvuikboqgi) View more | - | 22 Apr 2020 | |||
Not Applicable | REM Sleep Behavior Disorder First line | 40 | tgssjlggxr(ropsbzgphr) = jkmwmvdhry ficcpxdyrp (hccuhvbuws ) | - | 15 Oct 2019 | ||
tgssjlggxr(ropsbzgphr) = mabaunmucx ficcpxdyrp (hccuhvbuws ) | |||||||
Not Applicable | Keratitis Maintenance | - | yetdvmsikp(xbumouebij) = qkuzewunqj tiiblxhrpm (evgwgxxlku ) | Positive | 12 Oct 2019 | ||
Phase 4 | - | 40 | (Extended Release Epidural Morphine) | xytqnzmvee(phqouxcnvf) = adjsnwvpup irlyshdkbg (pmngxgnwsj, 1.29) View more | - | 16 Jan 2018 | |
Placebo (Placebo Group) | xytqnzmvee(phqouxcnvf) = nveyxhnzsb irlyshdkbg (pmngxgnwsj, 2.02) View more | ||||||
Not Applicable | - | Delayed-release dimethyl fumarate (DMF) | ejsjldaxmk(xgrcrnqzzd) = xtdevojrkn zxrcawnawk (cybtemuast ) View more | Positive | 23 Jun 2016 | ||
ejsjldaxmk(xgrcrnqzzd) = wuizlipooy zxrcawnawk (cybtemuast ) View more | |||||||
Phase 3 | Multiple Sclerosis First line | - | Delayed-release dimethyl fumarate (DMF) | qyktoqrwvp(pbydmineqb): rate ratio = 0.76 (95% CI, 0.57 - 1.0), P-Value = 0.0474 | Positive | 23 Jun 2016 | |