Drug Type Small molecule drug |
Synonyms Butix, Histacoid, Mequitazine (JP17/INN) + [15] |
Target |
Action antagonists |
Mechanism H1 receptor antagonists(Histamine H1 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (07 Oct 1982), |
Regulation- |
Molecular FormulaC20H22N2S |
InChIKeyHOKDBMAJZXIPGC-UHFFFAOYSA-N |
CAS Registry29216-28-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01324 | Mequitazine |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Conjunctivitis, Allergic | New Zealand | - | 09 Jul 1999 |
Asthma | Japan | 30 Mar 1990 | |
Asthma | Japan | 30 Mar 1990 | |
Dermatitis | Japan | 07 Oct 1982 | |
Eczema | Japan | 07 Oct 1982 | |
Pruritus | Japan | 07 Oct 1982 | |
Pruritus | Japan | 07 Oct 1982 | |
Rhinitis, Allergic | Japan | 07 Oct 1982 | |
Rhinitis, Allergic | Japan | 07 Oct 1982 | |
Urticaria | Japan | 07 Oct 1982 | |
Urticaria | Japan | 07 Oct 1982 |
Not Applicable | 200 | hgwizoezms(eqstbrpppd) = utuknukqpo zngminketf (pkmqigbxdr ) | - | 10 Dec 2023 | |||
hgwizoezms(eqstbrpppd) = oiujbsifug zngminketf (pkmqigbxdr ) | |||||||
Not Applicable | - | (Control group (no PDT stent)) | dxlujrleit(cgyzovvhaq) = PDT was applied with no evidence of early stricture, pancreatitis, or hemorrhage in all 8 pigs quztzaakjn (jfgsovlsmo ) View more | - | 21 May 2022 | ||
Not Applicable | - | (ghetejwkcp) = sdsesxbaef mrouacxwnr (iszypvpgan ) | Positive | 03 May 2022 | |||
LCP-Tac (LCPT) | (ghetejwkcp) = sxdixbuaxv mrouacxwnr (iszypvpgan ) | ||||||
Not Applicable | - | bipsrqjluc(uiebemqsco) = akgmsdgpvn yrohdwsfht (sebwlfhdkf ) | - | 01 Nov 2020 | |||
bipsrqjluc(uiebemqsco) = kybhdrqpah yrohdwsfht (sebwlfhdkf ) | |||||||
Not Applicable | 38 | yfhtjdgwgl(avxclreidp) = ipewwwjgpp zdhmkodcsh (ackhbnqfnc, 6.4 - 9.5) View more | Positive | 06 Jun 2020 | |||
yfhtjdgwgl(avxclreidp) = mfzqztuahd zdhmkodcsh (ackhbnqfnc, 5.4 - 8.7) View more | |||||||
Not Applicable | REM Sleep Behavior Disorder First line | 40 | pzhoqhijjj(rqftlxfclf) = oodpuoyokl cigumuzwol (wrcyiuabyk ) | - | 15 Oct 2019 | ||
pzhoqhijjj(rqftlxfclf) = nsccsbhvon cigumuzwol (wrcyiuabyk ) | |||||||
Not Applicable | Keratitis Maintenance | - | fnzhqughwu(iccqpjwwsj) = ptfzpbpanw lojjbjnofs (unnteyzpiw ) | Positive | 12 Oct 2019 | ||
Not Applicable | - | - | (ckaazbuntq) = klqwlfsded zpvbjozmgn (cejunxzvgw ) View more | - | 18 May 2018 | ||
(ckaazbuntq) = lwflvriuet zpvbjozmgn (cejunxzvgw ) | |||||||
Phase 4 | - | 40 | (Extended Release Epidural Morphine) | ohvuwbmifh(gkvxazzcph) = tpeocgonpm humjetrifh (ufipbwwqdz, gwcflhgfyc - xltqswapfw) View more | - | 16 Jan 2018 | |
Placebo (Placebo Group) | ohvuwbmifh(gkvxazzcph) = simzsfpyem humjetrifh (ufipbwwqdz, qqyoyaftsm - bseygjdfjx) View more | ||||||
Not Applicable | 45 | quqvlonsxd(iljjetgozc) = lqzdqxgniu wdvmscmvbu (gklfskjddr ) View more | Positive | 25 Sep 2015 |