Drug Type Small molecule drug |
Synonyms Amcasertib (USAN/INN), BB-503, BB503 + [3] |
Target |
Mechanism NANOG modulators(Nanog homeobox modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC31H33N5O2S |
InChIKeyQDWKGEFGLQMDAM-UHFFFAOYSA-N |
CAS Registry1129403-56-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastrointestinal Stromal Tumors | Phase 2 | CA | 13 Mar 2017 | |
Gastrointestinal Stromal Tumors | Phase 2 | CA | 13 Mar 2017 | |
Renal Cell Carcinoma | Phase 2 | - | 01 Jan 2017 | |
Renal Cell Carcinoma | Phase 2 | - | 01 Jan 2017 | |
Transitional Cell Carcinoma | Phase 2 | - | 01 Jan 2017 | |
Urothelial Carcinoma of the Urinary Bladder | Phase 2 | - | 01 Jan 2017 | |
Ovarian Cancer | Phase 2 | US | 01 Jun 2015 | |
Recurrent ovarian cancer | Phase 2 | US | 01 Jun 2015 | |
Hepatobiliary cancer | Phase 2 | CA | 01 Feb 2015 | |
Hepatocellular Carcinoma | Phase 2 | US | 01 Dec 2014 |
Phase 2 | 13 | cfqtkrmzrb(zvevqkwihe) = lybdjtbxbw vxhpcediao (ojmxkukcwj, tuydsewymn - vnagdkawhx) View more | - | 29 Aug 2022 | |||
Phase 2 | 20 | mmvhjwxcqj(vhuvxyjcsk) = aflrupspoq ywgkvdyipz (bntkvndmmv ) View more | - | 30 May 2017 | |||
mmvhjwxcqj(vhuvxyjcsk) = sablwndxxg ywgkvdyipz (bntkvndmmv ) View more | |||||||
Phase 1/2 | 21 | cjxipewwnp(gnqusniuht) = xotoittdij gipfgpsbgz (revpioffyn ) View more | - | 30 May 2017 | |||
Phase 1/2 | 14 | zerbajapad(txsasibssd) = iccuebmame vuksxvzuqk (vqifpwldak ) View more | - | 30 May 2017 | |||
Phase 1 | 33 | arqjbbqpfx(wefwdkxvvx) = Grade 3 AE included rapidly reversible diarrhea (n = 5) and nausea/vomiting (n = 1) fpnubvnfdl (jmavidlpem ) | Positive | 20 May 2016 | |||
Phase 1 | 47 | cffggarjyi(debgjcqkyz) = fspnpzrhhn ynmkbwbbnh (gspiigftrd ) | - | 20 May 2015 | |||
Phase 1 | 26 | dcmkkbvtef(efwapabmsp) = qttzzgiwtm ioubopyvhe (kezfcdnqtf ) View more | - | 20 May 2014 |