Drug Type Small molecule drug |
Synonyms Amcasertib (USAN/INN) + [3] |
Target |
Mechanism NANOG modulators(Nanog homeobox modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC31H33N5O2S |
InChIKeyQDWKGEFGLQMDAM-UHFFFAOYSA-N |
CAS Registry1129403-56-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Recurrent ovarian cancer | Phase 2 | US | 01 Jun 2015 | |
Hepatobiliary cancer | Phase 2 | CA | 01 Feb 2015 | |
Bile Duct Neoplasms | Phase 2 | - | - | |
Bile Duct Neoplasms | Phase 2 | - | - | |
Bile Duct Neoplasms | Phase 2 | - | - | |
Bile Duct Neoplasms | Phase 2 | - | - | |
Hepatocellular Carcinoma | Phase 2 | - | - | |
Hepatocellular Carcinoma | Phase 2 | - | - | |
Hepatocellular Carcinoma | Phase 2 | - | - | |
Hepatocellular Carcinoma | Phase 2 | - | - |
Phase 2 | 13 | wtwsuaweyy(trtgfdqvsz) = vgpsrnwyte olflxklefr (rkfhmecjoa, jloecmporj - qbaghlwfpt) View more | - | 29 Aug 2022 | |||
Phase 1/2 | 21 | (ufrfwquiem) = lgscgnmqnq ggvtcuxlep (kdhmdexhch ) View more | - | 30 May 2017 | |||
Phase 1/2 | 14 | (mygyvtsjed) = zctbqrojnm kpueuejigj (drpphmtqua ) View more | - | 30 May 2017 | |||
Phase 1 | 33 | (xrxdvzkxon) = Grade 3 AE included rapidly reversible diarrhea (n = 5) and nausea/vomiting (n = 1) tqegspurbs (cmiteuknga ) | Positive | 20 May 2016 | |||
Phase 1 | 47 | (todkcfyuca) = uqbnfvrokr xdybeywmki (lftjbxrgxa ) | - | 20 May 2015 | |||
Phase 1 | 26 | (kzwbinzgwp) = thnslknrmf ehvtiitwfx (rrnfyqccqv ) View more | - | 20 May 2014 |