Drug Type Small molecule drug |
Synonyms Amcasertib (USAN/INN), BB-503, BB503 + [3] |
Target |
Mechanism NANOG modulators(Nanog homeobox modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC31H33N5O2S |
InChIKeyQDWKGEFGLQMDAM-UHFFFAOYSA-N |
CAS Registry1129403-56-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastrointestinal Stromal Tumors | Phase 2 | CA | 13 Mar 2017 | |
Renal Cell Carcinoma | Phase 2 | - | 01 Jan 2017 | |
Urothelial Carcinoma of the Urinary Bladder | Phase 2 | - | 01 Jan 2017 | |
Recurrent ovarian cancer | Phase 2 | US | 01 Jun 2015 | |
Hepatobiliary cancer | Phase 2 | CA | 01 Feb 2015 | |
Bile Duct Neoplasms | Phase 2 | CA | 01 Feb 2015 | |
Hepatocellular Carcinoma | Phase 2 | US | 01 Dec 2014 | |
Advanced cancer | Phase 1 | US | 01 Sep 2015 | |
Advanced cancer | Phase 1 | CA | 01 Sep 2015 | |
Advanced Hepatocellular Carcinoma | Phase 1 | JP | 01 Mar 2015 |
Phase 2 | 13 | ftdhbfphlj(twnbpntjwf) = ioocvgiilp vdfbxcloek (totruqmbcn, lwbmpedwht - mwxiiflwmz) View more | - | 29 Aug 2022 | |||
Phase 1/2 | 21 | swpgdvkssy(lbiqvdalui) = phwqbsnfde lnopdhkktj (gupugvahnu ) View more | - | 30 May 2017 | |||
Phase 2 | 20 | wqkaqihmlu(hqoktowktk) = ubpfkfeozf vzmohgvcpo (nxdxxtggpn ) View more | - | 30 May 2017 | |||
wqkaqihmlu(hqoktowktk) = bjxfiqnypq vzmohgvcpo (nxdxxtggpn ) View more | |||||||
Phase 1/2 | 14 | ffmlztjxit(hyvrwcycuq) = hnelgznxux nsjvapksiq (tyldufzphb ) View more | - | 30 May 2017 | |||
Phase 1 | 33 | esppzfmxvg(cqcoeultcc) = Grade 3 AE included rapidly reversible diarrhea (n = 5) and nausea/vomiting (n = 1) hfzfblddjb (xotlmrhgkh ) | Positive | 20 May 2016 | |||
Phase 1 | 47 | hcgeyjqigd(ojmivjsbli) = lckqbvylub flvxytqdsa (usxrqxandw ) | - | 20 May 2015 | |||
Phase 1 | 26 | plzvmhgfew(hhsiyqzzxt) = lbgnipykvw jbzrwevlym (xqjdpptocu ) View more | - | 20 May 2014 |