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Last update 31 Jul 2025
HSK-42360
Last update 31 Jul 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms HSK42360 |
Target |
Action inhibitors |
Mechanism BRAF inhibitors(Serine/threonine-protein kinase B-raf inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with HSK-42360NCT06536400
A Phase I, Open-label, Dose-escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic of HSK42360 in Patients With BRAF V600 Mutation Locally Advanced or Metastatic Solid Tumors
CTR20252766
评价HSK42360片在BRAF V600突变的儿童恶性脑肿瘤患者中的安全性、耐受性以及药代动力学的I期临床研究
[Translation] A phase I clinical study to evaluate the safety, tolerability and pharmacokinetics of HSK42360 tablets in children with malignant brain tumors with BRAF V600 mutations
100 Clinical Results associated with HSK-42360
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100 Translational Medicine associated with HSK-42360
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100 Patents (Medical) associated with HSK-42360
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100 Deals associated with HSK-42360
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| BRAF V600 mutation-positive brain cancer | Phase 1 | China | 23 Jul 2025 | |
| BRAF mutation Solid Tumors | Phase 1 | China | 25 Jun 2024 | |
| Brain Cancer | Phase 1 | China | 25 Jun 2024 | |
| Brain metastases | Phase 1 | China | 25 Jun 2024 | |
| Central Nervous System Neoplasms | Phase 1 | China | 25 Jun 2024 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | China | 25 Jun 2024 | |
| BRAF V600 mutation-positive Neoplasms | Phase 1 | China | 21 Jun 2024 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | BRAF mutation Solid Tumors BRAF V600 mutations | 17 | ojzgzfsenb(pdobwtsfxe) = increased creatinine and increased ALT cttnqeuxqn (kyvawkwwxp ) View more | Positive | 30 May 2025 |
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